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Customer Quotations

Dr Hon Leong

Dr Hon Leong

London Regional Cancer Program Ontario, Canada

"We have access to other flow cytometers but our microvesicle work demands the sub-micron sensitivity and resolution only offered by ApogeeFlow's A50-Micro. The technical support from ApogeeFlow has always been prompt and effective and the volumetric fluidics and alignment free optics make it easy to use, but above all we chose the A50-Micro because its resolution and sensitivity is outstanding compared to other flow cytometers."

Silvia Montoro-García, PhD

Silvia Montoro-García, PhD

Postdoctoral Research Fellow
1. Centre for Cardiovascular Sciences, University of Birmingham (UK)
2. Department of Cardiology, Hospital Universitario Virgen de la Arrixaca (Murcia, Spain)

"I started my postdoctoral activity at the Centre for Cardiovascular Sciences (University of Birmingham, UK) in June 2010. My main motivations were to identify the biological value of microvesicles in thrombosis and endothelial dysfunction - especially in the context of atherothrombosis. Microparticle (MPs) analysis is very tricky as their small surface poses a problem for discrimination and labelling. My expertise comprises work with different flow cytometers for MPs. Among all the possibilities, we decided to purchase the ApogeeFlow A50-Micro due to its remarkable discrimination of small particles and due to its volumetric sampling system which avoids the need for counting beads. We have developed a new flow cytometric methodology representing a highly specific and reproducible approach when used with the A50-Micro high resolution flow cytometer (CV<6%). The technical support from ApogeeFlow has allowed the fast and efficient deployment of this technique here in Birmingham, which now represents a core technique that we apply on clinical studies of MPs and which is the focus of collaborations with several groups interested in the field."

Dr Stefano Amalfitano

Dr Stefano Amalfitano

Istituto di Ricerca Sulle Acque (IRSA) del CNR Rome, Italy

"We spent considerable time deciding among all the cytometers on the market. In the end, our choice was ApogeeFlow's A50-Micro. After about two years of use, testing and comparing, I can still say it was the right choice, at least for our research field (aquatic microbiology). It is a powerful and versatile machine for routine analysis and the portability and optical stability are added benefits."

University of Trento

Paola Foladori

University of Trento, Department of Civil and Environmental Engineering

Laura Bruni

Autonomous Province of Trento, Agency for the Treatment of Waste Water

"Our 'A40-Micro' flow cytometer gives the performance we need for measuring small bacteria, assessing their viability and absolute count. It has proven very reliable. After many years of use, we appreciate the high sensitivity not only of the fluorescence signals (for example viability assessment), but also of the light scatter signals."

Researcher, CNRS, France

"The ApogeeFlow A50-Micro has been designed for microbiological applications. It is thus optimized for very small particles such as marine bacteria and viruses. You can [install] a UV laser, very valuable for the analysis of bacteria thanks to dyes such as DAPI or Hoechst. The software is easy to manipulate and very intuitive."

Dutch researcher.

"To be honest, I am truly impressed by both the performance and the solidity of the A50-Micro. To my experience, detection of 100 nm polystyrene beads, after shipping and without optical alignment, is far from trivial for a flow cytometer. I believe there is even room for subtle improvements to optimize the lower detection limit for scattering, for example by illuminating with a 405 nm laser."

Publications

Publication
Authors
Title
Date
Brain, Behavior, and Immunity
Volume 123, January 2025, Pages 422-441
View Paper
Zhucheng Lin, Xuan Luo, Jason R. Wickman, Deepa Reddy, Jason T. DaCunza, Richa Pande, Yuzhen Tian, Ezgi E. Kasimoglu, Vivian Triana, Jingyun Lee, Cristina M. Furdui, Desmond Pink, Ahmet Sacan, Seena K. Ajit
Inflammatory pain resolution by mouse serum-derived small extracellular vesicles
2025
Alzheimer's Dement. 2024;1-13
View paper
Dayarathna T, Roseborough AD, Gomes J, et al.
Nanoscale flow cytometry-based quantification of blood-based extracellular vesicle biomarkers distinguishes MCI and Alzheimer's disease
2024
Cytometry. 2023;103(8):670-83
View paper
Pink D, Basu A, Wong M, Pham D, Valencia J, Triana V, et al.
Antibody titrations are critical for microflow cytometric analysis of extracellular vesicles
2023
Neurobiology of Disease
Volume 177, February 2023, 106001
View paper
A.D. Roseborough, Y. Zhu, L. Zhao, S.R. Laviolette, S.H. Pasternak, S.N. Whitehead
Fibrinogen primes the microglial NLRP3 inflammasome and propagates pro-inflammatory signaling via extracellular vesicles: Implications for blood-brain barrier dysfunction
2023
Journal of Neuroinflammation
View paper
A.D.Roseborough, S.J.Myers, R.Khazaee, Y. Zhu, L.Zhao, E.Iorio, F.M.Elahi, S. H.Pasternak and S.N.Whitehead
Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model
2023
Neurobiology of Disease 177 (2023) 106001
View paper
A.D. Roseborough, Y. Zhu, L. Zhao, S.R. Laviolette, S.H. Pasternak, S.N. Whitehead
Fibrinogen primes the microglial NLRP3 inflammasome and propagates pro-inflammatory signaling via extracellular vesicles: Implications for blood-brain barrier dysfunction
2023
ACS Earth Space Chem
View paper
Serge Nader, Alexandre Baccouche, Fiona Connolly, Maya Abou-Ghanem, Sarah A. Styler, John D. Lewis, Desmond Pink, and Sheref S. Mansy
Model Atmospheric Aerosols Convert to Vesicles upon Entry into Aqueous Solution
2022
Mol Oncol. 2022 Dec 15
DOI: 10.1002/1878-0261.13362
View paper
Robert J Paproski , Desmond Pink , Deborah L Sosnowski , Catalina Vasquez, John D Lewis
Building predictive disease models using extracellular vesicle microscale flow cytometry and machine learning
2022
PubMed PMID: 36408626
DOI: 10.1042/BSR20222185
View paper
Roberto Villalobos-Labra , Ricky Liu , Floor Spaans , Tamara Saez , Anita Quon, Michael Wong , Desmond Pink , John Lewis , Manu Vatish , Sandra T Davidge, Christy-Lynn M Cooke
Placenta-Derived Extracellular Vesicles from Preeclamptic and Healthy Pregnancies Impair ex vivo Vascular Endothelial Function
2022
Nanoscale, 2022, 14, 9781
Yohan Kim, Edwin van der Pol, Ali Arafa, Ishwor Thapa, Cameron J. Britton, Jorgena Kosti, Siyang Song, Vidhu B. Joshi, Ree M. Erickson, Hesham Alie, Fabrice Lucien
Calibration and standardization of extracellular vesicle measurements by flow cytometry for translational prostate cancer research
2022
Biomedicines 2021, 9, 124.
View paper
Jaco Botha, Haley R. Pugsley, Aase Handberg
Conventional, High-Resolution and Imaging Flow Cytometry: Benchmarking Performance in Characterisation of Extracellular Vesicles
2021
Platelets31.2 (2020): 206-214.
Rosinska, Justyna, et al.
"Effect of acetylsalicylic acid intake on platelet derived microvesicles in healthy subjects."
2020
PLoS ONE 15(8)
Palviainen M, Saraswat M, Varga Z, Kitka D, Neuvonen M, Puhka M, et al.
Extracellular vesicles from human plasma and serum are carriers of extravesicular cargo. Implications for biomarker discovery.
2020
Cells, 2020
J Karkowska-Kuleta, K Kulig, E Karnas, E Zuba-Surma
Characteristics of Extracellular Vesicles Released by the Pathogenic Yeast-Like Fungi Candida glabrata, Candida parapsilosis and Candida tropicalis
2020
bioRxiv (2020).
Cooper, Tyler T., et al.
"Ultrafiltration Segregates Tissue Regenerative Stimuli Harboured Within and Independent of Extracellular Vesicles."
2020
Gastroenterology (2020)
Dasgupta D et al.
IRE1A Stimulates Hepatocyte-derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis
2020
Front. Oncol., 04 June 2020
L. G. Rikkert et al.
Cancer-ID: Toward Identification of Cancer by Tumor-Derived Extracellular Vesicles in Blood.
2020
Brain. 2020 May 1;143(5):1476-1497.
Min Guo et al.
Microglial Exosomes Facilitate synuclein Transmission in Parkinson's Disease.
2020
PLoS ONE 15(6): e0233443.
Rikkert LG, de Rond L, van Dam A, van Leeuwen TG, Coumans FAW, de Reijke TM, et al.(2020)
Detection of extracellular vesicles in plasma and urine of prostate cancer patients by flow cytometry and surface plasmon resonance imaging.
2020
Platelets, 2020, 31(1): 26-32.
Gasecka A, Nieuwland R, Budnik M, et al.
Randomized controlled trial protocol to investigate the antiplatelet therapy effect on extracellular vesicles (AFFECT EV) in acute myocardial infarction[J].
2020
bioRxiv, 2020
Maia J, Batista S, Couto N, et al.
Population Analysis of Extracellular Vesicles in Microvolumes of Biofluids[J].
2020
Neuro-Oncology, Volume 22, Issue 7, July 2020, Pages 967-978
Benjamin T. Himes et al.
The role of extracellular vesicles and PD-L1 in glioblastoma-mediated immunosuppressive monocyte induction.
2020
Mitochondrion 8 August 2020
Olivia R.Stephens et al.
Characterization and origins of cell-free mitochondria in healthy murine and human blood.
2020
Cell Death Dis 11, 677 (2020).
Gidlof, O., Bader, K., Celik, S. et al.
Inhibition of the long non-coding RNA NEAT1 protects cardiomyocytes from hypoxia in vitro via decreased pri-miRNA processing.
2020
BMC Ophthalmology volume 20, Article number: 233 (2020)
Zhong-Fang Yuan et al.
MicroRNA-182-5p protects human lens epithelial cells against oxidative stress-induced apoptosis by inhibiting NOX4 and p38 MAPK signalling.
2020
Colloids and Surfaces B: Biointerfaces (2020)
Hou Y-chen, Li J-an, Zhu S-jie, Cao C, Tang J-nan, Zhang J-ying, Guan S-kang
Tailoring of cardiovascular stent material surface by immobilizing exosomes for better pro-endothelialization function
2020
Desmond Pink, Michael Wong, Diana Pham, Renjith Pillai , Leanne Stifanyk, Sylvia Koch, Rebecca Hiebert, Oliver Kenyon, John Lewis
Performance Qualification for Micro Flow Cytometers: Understanding technical limitations to improve your research
Jul-20
THE JOURNAL OF UROLOGY 1 Apr 2019
Fabrice Lucien-Matteoni et al.
NEXT-GENERATION LIQUID BIOPSIES USING EXTRACELLULAR VESICLE DETECTION BY NANOSCALE FLOW CYTOMETRY.
2019
Journal of hepatology, 2019, 71(6): 1193-1205.
Guo Q, Furuta K, Lucien F, et al.
Integrin 1-enriched extracellular vesicles mediate monocyte adhesion and promote liver inflammation in murine NASH[J].
2019
ournal of extracellular vesicles, 2019, 8(1): 1643671
de Rond L, Libregts S, Rikkert L G, et al.
Refractive index to evaluate staining specificity of extracellular vesicles by flow cytometry[J].
2019
Journal of extracellular vesicles, 2019, 8(1): 1629865
Zeng Y, Yao X, Liu X, et al.
Anti-angiogenesis triggers exosomes release from endothelial cells to promote tumor vasculogenesis[J].
2019
Journal of diabetes research, 2019
Hohendorff J, Drozdz A, Borys S, et al.
Effects of Negative Pressure Wound Therapy on Levels of Angiopoetin-2 and Other Selected Circulating Signaling Molecules in Patients with Diabetic Foot Ulcer[J].
2019
The Journal of Immunology, 2019, 203(7): 1961-1972.
Hao Q, Gudapati V, Monsel A, et al.
Mesenchymal Stem Cell Derived Extracellular Vesicles Decrease Lung Injury in Mice[J].
2019
International Society for Extracellular Vesicles Annual Meeting 2019. 2019, 8(Suppl. 1).
Rasmussen R W, Botha J, Sanden M, et al.
Lipoprotein particles can be detected by high-resolution flow cytometry and potentially interfere with EV characterization[C]
2019
Transfusion, 2019, 59(1): 134-145.
Wirtz M R, Jurgens J, Zuurbier C J, et al.
Washing or filtering of blood products does not improve outcome in a rat model of trauma and multiple transfusion[J].
2019
The Journal of Urology, 2019, 201(Supplement 4): e179-e179.
Lucien-Matteoni* F, Gomes J, Brar H, et al.
Mp13-07 next-generation liquid biopsies using extracellular vesicle detection by nanoscale flow cytometry[j].
2019
The Prostate, 2019, 79(15): 1767-1776.
Joncas F H, Lucien F, Rouleau M, et al.
Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients[J].
2019
van Manen L, Peters A L, van der Sluijs P M, et al.
Clearance and phenotype of extracellular vesicles after red blood cell transfusion in a human endotoxemia model[J].
2019
European Heart Journal, 2019, 40(Supplement_1): ehz747. 0073.
Gasecka A, Nieuwland R, Budnik M, et al.
257 Ticagrelor decreases concentrations of prothrombotic extracellular vesicles compared to clopidogrel[J].
2019
Frontiers in oncology, 2019, 9: 651.
Cumba Garcia L M, Peterson T E, Cepeda M A, et al.
Isolation and analysis of plasma-derived exosomes in patients with glioma[J].
2019
Oncotarget, 2019, Vol. 10, (No. 10), pp: 1045-1055.
Lucien F, Lac V, Billadeau D D, et al.
Glypican-1 and glycoprotein 2 bearing extracellular vesicles do not discern pancreatic cancer from benign pancreatic diseases[J].
2019
Microcirculation, 2019, 26(1): e12515.
Li B, Li L, Zhang Q, et al.
Effects of tumor necrosis factor induced exosomes on the endothelial cellular behavior, metabolism and bioenergetics[J].
2019
Clinical Kidney Journal, 2019.
Uil M, Hau C M, Ahdi M, et al.
Cellular origin and microRNA profiles of circulating extracellular vesicles in different stages of diabetic nephropathy[J].
2019
Hepatology communications, 2019, 3(9): 1235-1249.
Li J, Liu H, Mauer A S, et al.
Characterization of cellular sources and circulating levels of extracellular vesicles in a dietary murine model of nonalcoholic steatohepatitis[J].
2019
Thrombosis research, 2019, 176: 18-26.
Rosiska J, Ambrosius W, Maciejewska J, et al.
Association of platelet-derived microvesicles and their phenotypes with carotid atherosclerosis and recurrent vascular events in patients after ischemic stroke[J].
2019
Journal of extracellular vesicles, 2019, 8(1): 1688936.
Berckmans R J, Lacroix R, Hau C M, et al.
Extracellular vesicles and coagulation in blood from healthy humans revisited[J].
2019
The Prostate, 2019, 79(6): 592-603.
Padda R S, Deng F K, Brett S I, et al.
Nanoscale flow cytometry to distinguish subpopulations of prostate extracellular vesicles in patient plasma[J].
2019
Thorax, 2019, 74(1): 43-50.
Park J, Kim S, Lim H, et al.
Therapeutic effects of human mesenchymal stem cell microvesicles in an ex vivo perfused human lung injured with severe E. coli pneumonia[J].
2019
Artificial Cells, Nanomedicine, and Biotechnology, (2019) 47:1, 2918-2929
Rui Ren et al.
Bone marrow mesenchymal stem cell-derived exosome uptake and retrograde transport can occur at peripheral nerve endings
2019
J. Vis. Exp. (144), e59128, (2019).
Balbi, C., Bolis, S., Vassalli, G., Barile, L.
Flow Cytometric Analysis of Extracellular Vesicles from Cell-conditioned Media.
2019
Proteomes. 2019 Apr 25;7(2):17
Helena Kupcova Skalnikova et al.
Isolation and Characterization of Small Extracellular Vesicles from Porcine Blood Plasma, Cerebrospinal Fluid, and Seminal Plasma.
2019
Curr Protoc Stem Cell Biol. 2019 Feb;48(1):e76.
Cansu Gorgun et al.
Isolation and Flow Cytometry Characterization of Extracellular-Vesicle Subpopulations Derived from Human Mesenchymal Stromal Cells.
2019
HREBA.CC-18-0241 Version 2.0 April 10 2019
Adrian Fairey et al.
Clinical Validation of ClarityDX Prostate as a reflex test to PSA to refine the prediction of clinically significant prostate cancer. APCaRI-05
2019
Biomacromolecules 2019, 20, 9, 3592-3600
Jiwei Cui et al.
Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake.
2019
Pharmacological Research 141 (2019) 214-223
Maryam Baeeri et al.
-Lipoic acid prevents senescence, cell cycle arrest, and inflammatory cues in fibroblasts by inhibiting oxidative stress.
2019
Adv. Healthcare Mater. 2019
Jiwei Cui et al.
Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies.
2019
Mutat Res Gen Tox En 845 (2019)
Alena Opattova et al.
Ganoderma Lucidum induces oxidative DNA damage and enhances the effect of 5-Fluorouracil in colorectal cancer in vitro and in vivo.
2019
Journal of Controlled Release 307 (2019) 355-367
Matthew Faria et al.
Revisiting cell particle association in vitro: A quantitative method to compare particle performance.
2019
Iran J Basic Med Sci 2019; 22:445-451
Mohammadi P, Rahimifard M, Baeeri M, Abdollahi M, Mostafalou S.
Mechanistic assessment of cadmium toxicity in association with the functions of estrogen receptors in the Langerhans islets.
2019
J Thromb Haemost. 2019 Dec 12 doi: 10.1111/jth.14689
Gasecka A, Nieuwland R, Budnik M, Dignat-George F, Eyileten C, Harrison P, Lacroix R, Leroyer A, Opolski G, Pluta K, van der Pol E, Postua M, Siljander P, Siller-Matula JM, Filipiak KJ
Ticagrelor attenuates the increase of extracellular vesicle concentrations in plasma after acute myocardial infarction compared to clopidogrel
Dec-19
Platelets
Poznan University of Medical Sciences, Poznan, Poland: Justyna Rosinska, Joanna Maciejewska, Robert Narozny, Krystyna Osztynowicz, Beata Raczak, Slawomir Michalak, Cezary Watala, Wojciech Kozubski, Maria Lukasik
Effect of acetylsalicylic acid intake on platelet derived microvesicles in healthy subjects
Mar-19
Thrombosis Research
Poznan University of Medical Sciences, Poznan, Poland: Justyna Rosinska, Wojciech Ambrosius, Joanna Maciejewska, Robert Narozny, Wojciech Kozubski, Maria Lukasik
Association of platelet-derived microvesicles and their phenotypes with carotid atherosclerosis and recurrent vascular events in patients after ischemic stroke
Feb-19
International Journal of Medical Sciences 2019, 16(2): 264-275 doi: 10.7150/ijms.28580
Bernadeta Chyrchel, Anna Drod, Dorota Dugosz, Ewa Stpie, Andrzej Surdacki
Platelet Reactivity And Circulating Platelet-Derived Microvesicles Are Differently Affected By P2Y12 Receptor Antagonists
Jan-19
Transfusion. 2018 Jun;58(6):1486-1493
Anna L. Peters et al.
Transfusion of autologous extracellular vesicles from stored red blood cells does not affect coagulation in a model of human endotoxemia.
2018
Int Orthop. 2018 Dec;42(12):2865-2872.
Ye Zhao et al.
Synovial fluid-derived exosomal lncRNA PCGEM1 as biomarker for the different stages of osteoarthritis.
2018
bioRxiv Apr. 29, 2018
Desmond Pink, Julien Donnelier, John Lewis, Janice E. A. Braun.
Cargo-Loading of Misfolded Proteins into Extracellular Vesicles: The Role of J Proteins.
2018
Journal of Thrombosis and Haemostasis Volume 16, Issue 8 (2018)
Z. Varga et al.
Hollow organosilica beads as reference particles for optical detection of extracellular vesicles.
2018
bioRxiv, 2018: 476226.
Russell J C, Merrihew G E, Robbins J E, et al.
Isolation and characterization of extracellular vesicles from Caenorhabditis elegans for multi-omic analysis[J].
2018
Sci Rep. 2018; 8: 5426.
Ferenc Kovics et al.
The impact of circulating preeclampsia-associated extracellular vesicles on the migratory activity and phenotype of THP-1 monocytic cells.
2018
Arizona State University, 2018.
Zhong Z.
Molecular Profiling Plasma Extracellular Vesicles from Breast Cancer Patients[D].
2018
Frontiers in cardiovascular medicine, 2018, 5: 156.
Sanden M, Botha J, Nielsen M R S, et al.
BLTR1 and CD36 expressing microvesicles in atherosclerotic patients and healthy individuals[J].
2018
International journal of nanomedicine 13 (2018): 1653.
Dabrowska, Sylwia, et al.
"Imaging of extracellular vesicles derived from human bone marrow mesenchymal stem cells using fluorescent and magnetic labels."
2018
British Journal of Biomedical Science just-accepted (2018): 1-19.
Heitmar, R., et al.
"The relationship of systemic markers of haemostasis with retinal blood vessel responses in cardiovascular disease and/or diabetes."
2018
Journal of Thrombosis and Haemostasis (2018).
Yu, Y., et al.
"Extracellular vesicles from human saliva promote haemostasis by delivering coagulant tissue factor to activated platelets."
2018
Biochemical and biophysical research communications, 2018, 503(3): 1278-1283.
Zhang J, Wang W, Chen S, et al.
Distinct non-invasive evaluation values of tumor-derived cell-free microRNAs, circulating microvesicles and exosomal microRNAs after renal carcinoma cryoablation[J].
2018
Thrombosis and haemostasis, 2018, 118(06): 990-1000.
Yu Y, Buing A N, Hau C M, et al.
Tissue Factor Coagulant Activity is Regulated by the Plasma Membrane Microenvironment[J].
2018
Journal of extracellular vesicles, 2018, 7(1): 1458574.
Zhong Z, Rosenow M, Xiao N, et al.
Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion[J].
2018
British Journal of Biomedical Science, 2018 (just-accepted): 1-19.
Heitmar R, Nicholl P, Lee B, et al.
The relationship of systemic markers of haemostasis with retinal blood vessel responses in cardiovascular disease and/or diabetes[J].
2018
Breast cancer research and treatment, 2018: 1-10.
Garre E G, Gil G L, Garcia S M, et al.
Circulating small-sized endothelial microparticles as predictors of clinical outcome after chemotherapy for breast cancer: an exploratory analysis[J].
2018
Thromb Haemost. 2018 Sep;118(9):1612-1624.
Janice Gomes et al.
Analytical Considerations in Nanoscale Flow Cytometry of Extracellular Vesicles to Achieve Data Linearity.
2018
Synaptosomes. Humana Press, New York, NY, 2018: 297-310.
Postupna N O, Latimer C S, Keene C D, et al.
Flow Cytometric Evaluation of Crude Synaptosome Preparation as a Way to Study Synaptic Alteration in Neurodegenerative Diseases[M]
2018
J Thromb Haemost 2018; 16:1236-45.
van der Pol E, Sturk A, van Leeuwen T, Nieuwland R, Coumans F, for the ISTH-SSC-VB Working group.
Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation.
2018
RNA biology, 2018 (just-accepted): 1-21.
Guo T, Han W, She Q.
Tolerance of Sulfolobus SMV1 virus to the immunity of IA and III-B CRISPR-Cas systems in Sulfolobus islandicus[J].
2018
Use of Nanoparticles in Neuroscience. Humana Press, New York, NY, 2018: 251-267.
Kaszewski J, Kiebik P, Soska-Zielonka A, et al.
Long-Term Organism Distribution of Microwave Hydrothermally Synthesized ZrO 2: Pr Nanoparticles[M]
2018
ACS applied materials & interfaces, 2018.
Cherepanov P V, Rahim M A, Bertleff-Zieschang N, et al.
Electrochemical Behavior and Redox-Dependent Disassembly of Gallic Acid/FeIII Metal Phenolic Networks[J].
2018
Nanoscale, 2018.
Bertucci A, Guo J, Oppmann N, et al.
Probing transcription factor binding activity and downstream gene silencing in living cells with a DNA nanoswitch[J].
2018
Toxicology and applied pharmacology, 2018, 342: 86-98.
Sanadgol N, Golab F, Mostafaie A, et al.
Low, but not high, dose triptolide controls neuroinflammation and improves behavioral deficits in toxic model of multiple sclerosis by dampening of NF-B activation and acceleration of intrinsic myelin repair[J].
2018
Polymer Chemistry, 2018.
Zhang Y, Jiang Q, Wojnilowicz M, et al.
Acid-sensitive poly (-cyclodextrin)-based multifunctional supramolecular gene vector[J].
2018
Small 2018, 1802342
Quinn A. Besford et al.
Self-Assembled Metal Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles.
2018
Magdalena Surmana, Dorota Hoja-ukowicza, Sabina Szweda, Anna Drodb, Ewa Stpie, Magorzata Przybyio
Human melanoma-derived ectosomes are enriched with specific glycan epitopes
Jun-18
Preprint: View paper
Desmond Pink, Julien Donnelier, John Lewis, Janice E.A. Braun
Cargo-Loading of Misfolded Proteins into Extracellular Vesicles: The Role of J Proteins
Apr-18
J. of Thrombosis & Haemostasis, 16: 1-10 doi: 10.1111/jth.14009
E . Van Der Pol, A. Sturk, T. Van Leeuwen, R. Nieuwland, F. Coumans for the ISTH-SSC-VB Working Group
Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation
Feb-18
American Association for Clinical Chemistry doi:10.1373/clinchem.2017.278978
Leonie de Rond, Edwin van der Pol, Chi M. Hau, Zoltan Varga, Auguste Sturk, Ton G. van Leeuwen, Rienk Nieuwland, Frank A.W. Coumans
Comparison of Generic Fluorescent Markers for Detection of Extracellular Vesicles by Flow Cytometry
Feb-18
Nanomedicine: Nanotechnology, Biology, and Medicine doi:10.1016/j.nano.2017.12.012
Edwin van der Pol, Leonie de Rond, Frank A.W. Coumans, Elmar L. Gool, Anita N. Bing, Auguste Sturk, Rienk Nieuwland, Ton G. van Leeuwen
Absolute sizing and label-free identification of extracellular vesicles by flow cytometry
Jan-18
Cancer Research, 2017, 77(1): 3-13.
Paproski R J, Jovel J, Wong G K S, et al.
Enhanced detection of cancer biomarkers in blood-borne extracellular vesicles using nanodroplets and focused ultrasound[J].
2017
Scientific reports, 2017, 7: 42741.
Domenyuk V, Zhong Z, Stark A, et al.
Plasma exosome profiling of cancer patients by a next generation systems biology approach[J].
2017
European Journal of Pharmaceutical Sciences, 2017, 98: 4-16.
Valkonen S, Van der Pol E, Bing A, et al.
Biological reference materials for extracellular vesicle studies[J].
2017
Translational Cancer Research, 2017, 6(3): 599-612.
Guo L, He B.
Extracellular vesicles and their diagnostic and prognostic potential in cancer[J].
2017
Clinical chemistry, 2017, 63(10): 1633-1641.
Gool E L, Stojanovic I, Schasfoort R B M, et al.
Surface plasmon resonance is an analytically sensitive method for antigen profiling of extracellular vesicles[J].
2017
2017
Pink D, Paproski R, Sosnowski D, et al.
Technical validation of a micro-flow cytometry platform for prostate cancer biomarker discovery [J].
2017
Journal of extracellular vesicles, 2017, 6(1): 1354645.
Lazaro-Ibez E, Neuvonen M, Takatalo M, et al.
Metastatic state of parent cells influences the uptake and functionality of prostate cancer cell-derived extracellular vesicles[J].
2017
Journal of thrombosis and thrombolysis, 2017, 43(1): 18-23.
Lau Y C, Xiong Q, Blann A D, et al.
Relationship between renal function and circulating microparticles, soluble P-selectin and E-selectin levels in atrial fibrillation[J].
2017
Transfusion, 2017, 57(6): 1459-1469.
Black A, Ors E, Kelsch R, et al.
Analysis of platelet derived extracellular vesicles in plateletpheresis concentrates: a multicenter study[J].
2017
Frontiers in cellular and infection microbiology, 2017, 7: 351.
Fleetwood A J, Lee M K S, Singleton W, et al.
Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles[J].
2017
Frontiers in immunology, 2017, 8: 1017.
Cecil J D, O'Brien-Simpson N M, Lenzo J C, et al.
Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo[J].
2017
Cancer Research Frontiers, 2017, 3(1): 83-111.
Tatischeff I.
Prostate Cancer under the Light of Tumor Cells-derived Extracellular Vesicles[J].
2017
The Prostate, 2017, 77(13): 1335-1343.
Brett S I, Lucien F, Guo C, et al.
Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples[J].
2017
2017
Brar H S.
Triple Positive Microparticles as a 'Liquid Biopsy' for Risk Stratification of Prostate Cancer[J].
2017
Extracellular Vesicles. Humana Press, New York, NY, 2017: 175-190.
Camacho V, Toxavidis V, Tigges J C.
Characterization of Extracellular Vesicles by Flow Cytometry[M]
2017
Drug testing and analysis, 2017.
Voss S C, Jaganjac M, Al Thani A M, et al.
Analysis of RBC Microparticles in stored whole blood bags - a promising marker to detect blood doping in sports? [J].
2017
2017
Pereira H M G, Sardela V F, Padilha M C, et al.
Report Sport doping and medicine[J]
2017
Int J Clin Exp Pathol. 2017; 10(8): 8383-8388.
Yingge Wang et al.
Circulating exosomes and exosomal lncRNA HIF1A-AS1 in atherosclerosis.
2017
Journal of Microcirculation, 2017, 27(2): 8-12
Zhang Honggang and others
Essential hypertensive rats plasma exosomes level and its correlation with microcirculation changes.
2017
J Thromb Haemost 2017; 15: 187-93.
Cointe S, Judicone C, Robert S, Mooberry MJ, Poncelet P, Wauben M, Nieuwland R, Key NS, Dignat-George F, Lacroix R.
Standardization of microparticle enumeration across different flow cytometry platforms: results of a multicenter collaborative workshop.
2017
Am J Pathol. 2017 Apr;187(4):884-895.
Nadia Postupna et al.
Human Striatal Dopaminergic and Regional Serotonergic Synaptic Degeneration with Lewy Body Disease and Inheritance of APOE 4.
2017
Drug Test Anal. 2017 Nov;9(11-12):1794-1798.
Sven Christian Voss et al.
Analysis of RBC-microparticles in stored whole blood bags - a promising marker to detect blood doping in sports?
2017
Virology, 2017, 505: 80-90.
Bonar M M, Tilton J C.
High sensitivity detection and sorting of infectious human immunodeficiency virus (HIV-1) particles by flow virometry[J].
2017
Methods, 2017.
Reyes J L Z, Aguilar H C.
Flow Virometry as a Tool to Study Viruses[J].
2017
Biomaterials Science, 2017.
Braunger J A, Bjrnmalm M, Isles N A, et al.
Interactions between circulating nanoengineered polymer particles and extracellular matrix components in vitro[J].
2017
ACS applied materials & interfaces, 2017, 9(39): 33683-33694.
4.Song D, Cui J, Sun H, et al.
Templated Polymer Replica Nanoparticles to Facilitate Assessment of Material-Dependent Pharmacokinetics and Biodistribution[J].
2017
Scientific reports, 2017, 7(1): 5686.
5.Smith E R, Hewitson T D, Cai M M X, et al.
A novel fluorescent probe-based flow cytometric assay for mineral-containing nanoparticles in serum[J].
2017
Biomacromolecules 2017, 18, 2, 431-439
Qiong Dai et al.
Cell-Conditioned Protein Coronas on Engineered Particles Influence Immune Responses.
2017
Biol Trace Elem Res. 2017 Jan;175(1):146-155.
Shermineh Moeini-Nodeh et al.
Functional Improvement in Rats' Pancreatic Islets Using Magnesium Oxide Nanoparticles Through Antiapoptotic and Antioxidant Pathways.
2017
Biomacromolecules 2017, 18, 2, 431-439
Qiong Dai et al.
Cell-Conditioned Protein Coronas on Engineered Particles Influence Immune Responses.
2017
International journal of nanomedicine, 2017, 12: 4519.
Novotna B, Herynek V, Rossner Jr P, et al.
The effects of grafted mesenchymal stem cells labeled with iron oxide or cobalt-zinc-iron nanoparticles on the biological macromolecules of rat brain tissue extracts[J].
2017
The American journal of pathology, 2017, 187(4): 884-895.
Postupna N, Latimer C S, Larson E B, et al.
Human Striatal Dopaminergic and Regional Serotonergic Synaptic Degeneration with Lewy Body Disease and Inheritance of APOE 4[J].
2017
Biol Trace Elem Res. 2017 Jan;175(1):146-155
Shermineh Moeini-Nodeh et al.
Functional Improvement in Rats Pancreatic Islets Using Magnesium Oxide Nanoparticles Through Antiapoptotic and Antioxidant Pathways.
2017
Food and chemical toxicology, 2017, 100: 8-23.
Baeeri M, Momtaz S, Navaei-Nigjeh M, et al.
Molecular evidence on the protective effect of ellagic acid on phosalone-induced senescence in rat embryonic fibroblast cells[J].
2017
Circulation Research January 5, 2018, Volume 122, Issue 1 doi: 10.1161/CIRCRESAHA.117.311769
Marta Adamiak, Ewa K Zuba-Surma et al.
Induced Pluripotent Stem Cell (iPSC)-Derived Extracellular Vesicles Are Safer and More Effective for Cardiac Repair than iPSCs
08-Nov-17
Polish Heart Journal e-ISSN: 1897-4279 doi: 10.5603/KP.a2017.0178
Aleksandra Gasecka, Edwin van der Pol, Rienk Nieuwland, Ewa Stepien
Extracellular vesicles in post-infarct ventricular remodelling
13-Sep-17
Transfusion doi:10.1111/trf.14109
Black A, Ors E, Kelsch R, Pereira M, Kamhieh-Milz J, Salama A, Fischer MB, Meyer E, Frey BM, Schmitz G
Analysis of platelet-derived extracellular vesicles in plateletpheresis concentrates: a multicenter study
Apr-17
Sci Rep. 2016; 6: 19328.
Carson T Gavin et al.
Novel Methods of Determining Urinary Calculi Composition: Petrographic Thin Sectioning of Calculi and Nanoscale Flow Cytometry Urinalysis.
2016
Journal of Thrombosis and Thrombolysis, 2016: 1-6.
Lau Y C, Xiong Q, Blann A D, et al.
Relationship between renal function and circulating microparticles, soluble P-selectin and E-selectin levels in atrial fibrillation[J].
2016
Transfusion, 2016, 56(12): 3012-3020.
Straat M, van Hezel M E, Bing A, et al.
Monocyte mediated activation of endothelial cells occurs only after binding to extracellular vesicles from red blood cell products, a process mediated by integrin[J].
2016
Journal of Thrombosis and Haemostasis, 2016.
Cointe S, Judicone C, Robert S, et al.
Standardization of microparticle enumeration across different flow cytometry platforms: results of a multicenter collaborative workshop[J].
2016
PloS one, 2016, 11(4): e0151967.
Cecil J D, O'Brien-Simpson N M, Lenzo J C, et al.
Differential Responses of Pattern Recognition Receptors to Outer Membrane Vesicles of Three Periodontal Pathogens[J].
2016
European Journal of Pharmaceutical Sciences, 2016.
Valkonen S, van der Pol E, Bing A, et al.
Biological reference materials for extracellular vesicle studies[J].
2016
Analyst, 2016, 141(2): 450-460.
Ko J, Carpenter E, Issadore D.
Detection and isolation of circulating exosomes and microvesicles for cancer monitoring and diagnostics using micro-/nano-based devices[J].
2016
Stem Cells, 2016, 34(3): 781-790.
Kerkel E, Laitinen A, Rbin J, et al.
Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells[J].
2016
Journal of extracellular vesicles, 2016, 5(1): 29254.
Higginbotham J N, Zhang Q, Jeppesen D K, et al.
Identification and characterization of EGF receptor in individual exosomes by fluorescence-activated vesicle sorting[J].
2016
-2016
Valkonen, S., van der Pol, E., Boing, A., Yuana, Y., Yliperttula, M., Nieuwland, R., Laitinen, S., Siljander, P.R.M.
Biological reference materials for extracellular vesicle studies
2016
Journal of Controlled Release (2016)
Scott Ferguson, Juliane Nguyen
Exosomes as therapeutics: The implications of molecular composition and exosomal heterogeneity
2016
Particle and Fibre Toxicology (2016) 13:13
Rodosthenis S. Rodosthenous et al.
Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals. Rodosthenous et al.
2016
Sci Rep. 2016; 6: 19328.
Carson T Gavin et al.
Novel Methods of Determining Urinary Calculi Composition: Petrographic Thin Sectioning of Calculi and Nanoscale Flow Cytometry Urinalysis.
2016
PLoS ONE 11(6): e0156940.
Rose JA, Wanner N, Cheong HI, Queisser K, Barrett P, Park M, et al.
(2016) Flow Cytometric Quantification of Peripheral Blood Cell -Adrenergic Receptor Density and Urinary Endothelial Cell Derived Microparticles in Pulmonary Arterial Hypertension.
2016
Journal of virology, 2016, 90(12): 5693-5699.
Uldahl K B, Jensen S B, Bhoobalan-Chitty Y, et al.
Life cycle characterization of Sulfolobus monocaudavirus 1, an extremophilic spindle-shaped virus with extracellular tail development[J].
2016
ACS Applied Materials & Interfaces, 2016, 8(35): 22914-22922.
Ju Y, Dai Q, Cui J, et al.
Improving Targeting of Metal Phenolic Capsules by the Presence of Protein Coronas[J].
2016
Langmuir, 2016, 32(14): 3532-3540.
Cui J, Hibbs B, Gunawan S T, et al.
Immobilized particle imaging for quantification of nano-and microparticles[J].
2016
Scientific reports, 2016, 6.
Gavin C T, Ali S N, Tailly T, et al.
Novel Methods of Determining Urinary Calculi Composition: Petrographic Thin Sectioning of Calculi and Nanoscale Flow Cytometry Urinalysis[J].
2016
Nanoscale, 2016, 8(23): 11924-11931.
Chen X, Cui J, Sun H, et al.
Analysing intracellular deformation of polymer capsules using structured illumination microscopy[J].
2016
Biomacromolecules, 2016, 17(3): 1205-1212.
Chen X, Yan Y, Mullner M, et al.
Shape-Dependent Activation of Cytokine Secretion by Polymer Capsules in Human Monocyte-Derived Macrophages[J].
2016
Biomacromolecules, 2016.
Ju Y, Cui J, Sun H, et al.
Engineered Metal-Phenolic Capsules Show Tunable Targeted Delivery to Cancer Cells[J].
2016
Langmuir, 2016, 32(42): 10995-11001.
Bjornmalm M, Faria M, Chen X, et al.
Dynamic Flow Impacts Cell Particle Interactions: Sedimentation and Particle Shape Effects[J].
2016
Particle and Fibre Toxicology (2016) 13:13
Rodosthenis S. Rodosthenous et al.
Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals. Rodosthenous et al.
2016
Small 2016, 12, No. 3, 371-380
Robert J. Paproski et al.
Porphyrin Nanodroplets: Sub-micrometer Ultrasound and Photoacoustic Contrast Imaging Agents.
2016
Small. 2016 Jan 20;12(3):371-80.
Robert J Paproski et al.
Porphyrin Nanodroplets: Sub-micrometer Ultrasound and Photoacoustic Contrast Imaging Agents.
2016
PLoS One, 2016, 11(6): e0157778.
Obruca S, Sedlacek P, Krzyzanek V, et al.
Accumulation of Poly (3-hydroxybutyrate) Helps Bacterial Cells to Survive Freezing[J].
2016
Journal of Nanoparticle Research, 2016, 18(4): 1-18.
Kaman O, D'dourkov T, Koktan J, et al.
Silica-coated manganite and Mn-based ferrite nanoparticles: a comparative study focused on cytotoxicity[J].
2016
Langmuir, 2016, 32(47): 12394-12402.
Cui J, Faria M, Bjornmalm M, et al.
A Framework to Account for Sedimentation and Diffusion in Particle Cell Interactions[J].
2016
Environmental toxicology and pharmacology, 2016, 42: 30-37.
Baghaei A, Solgi R, Jafari A, et al.
Molecular and biochemical evidence on the protection of cardiomyocytes from phosphine-induced oxidative stress, mitochondrial dysfunction and apoptosis by acetyl-l-carnitine[J].
2016
Biomacromolecules 2016, 17, 3, 1205-1212
Xi Chen et al.
Shape-Dependent Activation of Cytokine Secretion by Polymer Capsules in Human Monocyte-Derived Macrophages.
2016
Nature, Scientific Reports 6:36502 doi: 10.1038/srep36502
Golam Kibria, Erika K. Ramos, Katelyn E. Lee, Sarah Bedoyan, Simo Huang, Ravand Samaeekia, Jaffre J. Athman, Clifford V. Harding, Jan Lutvall, Lyndsay Harris, Cheryl L. Thompson & Huiping Liu
A rapid, automated surface protein profiling of single circulating exosomes in human blood
07-Nov-16
J Mol Med (2017) 95:205-220 doi 10.1007/s00109-016-1471-7
Sylwia Bobis-Wozowicz & Katarzyna Kmiotek & Karolina Kania & Elzbieta Karnas & Anna Labedz-Maslowska & Malgorzata Sekula & Sylwia Kedracka-Krok & Jacek Kolcz & Dariusz Boruczkowski & Zbigniew Madeja1 & Ewa K. Zuba-Surma
Diverse impact of xeno-free conditions on biological and regenerative properties of hUC-MSCs and their extracellular vesicles
16-Sep-16
PLoS One 2016 Jun 7;11(6):e0156940 doi: 10.1371/journal.pone.0156940
Jonathan A. Rose, Nicholas Wanner2, Hoi I. Cheong, Kimberly Queisser, Patrick Barrett, Margaret Park, Corrine Hite, Sathyamangla V. Naga Prasad, Serpil Erzurum, Kewal Asosingh
Flow Cytometric Quantification of Peripheral Blood Cell -Adrenergic Receptor Density and Urinary Endothelial Cell-Derived Microparticles in Pulmonary Arterial Hypertension
Jun-16
Vaccine doi:10.1016/j.vaccine.2016.03.067
Josef Vlasak, Van M. Hoanga, Sianny Christantia, Richard Pelusoa, Fengsheng Lib, Timothy D. Culp. Merck Research Labs
Use of flow cytometry for characterization of human cytomegalovirus vaccine particles.
Mar-16
Cytometry Part B 2016; 00B: 000-000. doi: 10.1002/cyto.b.21343
Wayne L. Chandler
Measurement of Microvesicle Levels in Human Blood Using Flow Cytometry.
Feb-16
Oncotarget. 2016 Feb 23;7(8):8839-49 doi: 10.18632/oncotarget.6983
Colleen N. Biggs1, Khurram M. Siddiqui, Ali A. Al-Zahrani1, Siddika Pardhan, Sabine I. Brett, Qiu Q. Guo, Jun Yang, Philipp Wolf, Nicholas E. Power, Paul N. Durfee, Connor D. MacMillan, Jason L. Townson, Jeffrey C. Brinker, Neil E. Fleshner, Jonathan I. Izawa, Ann F. Chambers, Joseph L. Chin and Hon S. Leong
Prostate extracellular vesicles in patient plasma as a liquid biopsy platform for prostate cancer using nanoscale flow cytometry.
Jan-16
Stem Cells, 2015, 33(9): 2748-2761
Bobis Wozowicz S, Kmiotek K, Sekula M, et al.
Human Induced Pluripotent Stem Cell Derived Microvesicles Transmit RNAs and Proteins to Recipient Mature Heart Cells Modulating Cell Fate and Behavior[J].
2015
Prostate cancer and prostatic diseases, 2015, 18(3): 213-220.
Brett S I, Kim Y, Biggs C N, et al.
Extracellular vesicles such as prostate cancer cell fragments as a fluid biopsy for prostate cancer[J].
2015
Transfusion, 2015, 55(9): 2184-2196.
Black A, Pienimaeki Roemer A, Kenyon O, et al.
Platelet derived extracellular vesicles in plateletpheresis concentrates as a quality control approach[J].
2015
J Neuropathol Exp Neurol. 2015 Jul; 74(7): 672-687.
Yue Yang, PhD et al.
Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease.
2015
Polym. Chem., 2015, 6, 6475-6487
D. Gu et al.
Amphiphilic core cross-linked star polymers as water-soluble, biocompatible and biodegradable unimolecular carriers for hydrophobic drugs.
2015
ACS Nano 2015, 9, 3, 2876-2885
Qiong Dai et al.
Monoclonal Antibody-Functionalized Multilayered Particles: Targeting Cancer Cells in the Presence of Protein Coronas.
2015
Biomacromolecules, 2015, 16(8): 2463-2474.
Shirbin S J, Ladewig K, Fu Q, et al.
Cisplatin-induced formation of biocompatible and biodegradable polypeptide-based vesicles for targeted anticancer drug delivery[J].
2015
ACS Nano 2015, 9, 2, 1571-1580
Jiwei Cui et al.
Engineering Poly(ethylene glycol) Particles for Improved Biodistribution.
2015
Langmuir. 2015 Aug 25;31(33):9054-60.
Mattias Bjrnmalm et al.
Flow-Based Assembly of Layer-by-Layer Capsules through Tangential Flow Filtration.
2015
Cell J. 2015; 17(2): 361-371.
Pedram S, Mohammadirad A, Rezvanfar MA, Navaei-Nigjeh M, Baeeri M, Abdollahi M.
On the protection by the combination of CeO2 nanoparticles and sodium selenite on human lymphocytes against chlorpyrifos-induced apoptosis in vitro.
2015
ACS nano, 2015, 9(2): 1294-1304.
Mullner M, Dodds S J, Nguyen T H, et al.
Size and rigidity of cylindrical polymer brushes dictate long circulating properties in vivo[J].
2015
ACS nano, 2015, 9(3): 2433-2444.
Gause K T, Yan Y, Cui J, et al.
Physicochemical and immunological assessment of engineered pure protein particles with different redox states[J].
2015
Chem. Sci., 2015, 6, 3505-3514
Huanli Sun et al.
The role of capsule stiffness on cellular processing.
2015
PLoS One. 2015; 10(7): e0131466
Manon Vinay et al.
Phage-Based Fluorescent Biosensor Prototypes to Specifically Detect Enteric Bacteria Such as E. coli and Salmonella enterica Typhimurium.
2015
STEM CELLS 2015
KERKEL E et al.
Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells (MSCs) Requires Co-operation with T Cells.
2015
J Neuropathol Exp Neurol 2015 July ; 74(7): 672-687. doi:10.1097/NEN.0000000000000207
Yue Yang, PhD1, C. Dirk Keene, MD, PhD1, Elaine R. Peskind, MD2,3, Douglas R. Galasko, MD4, Shu-Ching Hu, MD, PhD5, Eiron Cudaback, PhD1, Angela M. Wilson, MS1, Ge Li, MD, PhD2, Chang-En Yu, PhD6,7, Kathleen S. Montine, PhD1, Jing Zhang, MD, PhD1, Geoffrey S. Baird, MD, PhD1,8, Bradley T. Hyman, MD, PhD9, and Thomas J. Montine, MD, PhD1
Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease
Jul-15
STEM CELLS 2015;33:2748-2761 http://dx.doi.org/10.1002/stem.2078
Sylwia Bobis-Wozowicz, Katarzyna Kmiotek, Malgorzata Sekula, Sylwia Kedracka-Krok, Elzbieta Kamycka, Marta Adamiak, Urszula Jankowska, Anna Madetko-Talowska, Michal Sarna, Miroslaw Bik-Multanowski, Jacek Kolcz, Dariusz Boruczkowski, Zbigniew Madeja, Buddhadeb Dawn andEwa K. Zuba-Surma
Human Induced Pluripotent Stem Cell-Derived Microvesicles Transmit RNAs and Proteins to Recipient Mature Heart Cells Modulating Cell Fate and Behavior
Jun-15
Transfusion 55 (9) MAY 2015 doi: 10.1111/trf.13128
Anne Black, Annika Pienimaki-Romer, Oliver Kenyon, Gerd Schmitz
Platelet-derived extracellular vesicles in plateletpheresis concentrates as a quality control approach: VESICLES IN PLATELET CONCENTRATES
May-15
ASM Infection and Immunity doi: 10.1128/IAI.00198-15
Yannick R. Brunet, Ahmad Khodr, Laureen Logger, Laurent Aussel, Tim Mignot, Sylvie Rimsky, Eric Cascalesa.
H-NS Silencing of the Salmonella Pathogenicity Island 6-Encoded Type VI Secretion System Limits Salmonella enterica Serovar Typhimurium Interbacterial Killing.
Apr-15
J of AOAC International 2015
View paper 98.2, 371-378
Miller, Melinda; Ramsaroop, Shawn; Lopez, Chris; Brahmanda, Bharath
Vivione Bioscience RAPID-B E. coli O157 Test Kit and non-O157 STEC Test Kit Evaluation.
Apr-15
J of Extracellular Vesicles 2015 4: 25530
View paper
Vendula Pospichalova, Jan Svoboda, Zankruti Dave, Anna Kotrbova, Karol Kaiser, Dobromila Klemova, Ladislav Ilkovics, Ales Hampl, Igor Crha, Eva Jandakova, Lubos Minar, Vit Weinberger and Vitezslav Bryja
Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer.
Mar-15
Biomacromolecules 2015, 16, 807-814 doi: 10.1021/bm5017139
Yi Ju, Jiwei Cui, Markus Mullner, Tomoya Suma, Ming Hu, and Frank Caruso*
Engineering Low-Fouling and pH-Degradable Capsules through the Assembly of Metal-Phenolic Networks
Feb-15
J Extracell Vesicles. 2014; 3: 10.3402
Yuana Yuana et al.
Co-isolation of extracellular vesicles and high-density lipoproteins using density gradient ultracentrifugation.
2014
Cellular & molecular immunology, 2014, 11(6): 548-563.
Tannetta D, Dragovic R, Alyahyaei Z, et al.
Extracellular vesicles and reproduction promotion of successful pregnancy[J].
2014
Cancer Research, 2014, 74(19 Supplement): LB-177-LB-177.
Pink D B, Sosnowski D, Paproski R, et al.
Abstract LB-177: Handling of liquid biopsy samples can dramatically change the numbers of PSMA-positive microparticles[J].
2014
2014
Siddiqui K M.
Prostate Cancer Microparticles as a Next Generation Screening Tool for Prostate Cancer[J].
2014
Journal of extracellular vesicles, 2014, 3.
Yuana Y, Levels J, Grootemaat A, et al.
Co-isolation of extracellular vesicles and high-density lipoproteins using density gradient ultracentrifugation[J].
2014
American journal of clinical pathology, 2014, 142(3): 331-338.
Nelles N J, Chandler W L.
Platelet mapping assay interference due to platelet activation in heparinized samples[J].
2014
British journal of haematology, 2014, 166(4): 571-580.
Montoro Garcia S, Shantsila E, Hernndez Romero D, et al.
Small size platelet microparticles trigger platelet and monocyte functionality and modulate thrombogenesis via P-selectin[J].
2014
British Journal of Haematology, 2014, 166, 571-580
Silvia Montoro Garcia et al.
Small size platelet microparticles trigger platelet and monocyte functionality and modulate thrombogenesis via P-selectin.
2014
Langmuir, 2014, 30(21): 6286-6293.
Mullner M, Cui J, Noi K F, et al.
Surface-initiated polymerization within mesoporous silica spheres for the modular design of charge-neutral polymer particles[J].
2014
Biol Trace Elem Res (2014) 162:262-269
Parisa Shoae-Hagh et al.
Zinc Oxide Nanoparticles Reduce Apoptosis and Oxidative Stress Values in Isolated Rat Pancreatic Islets.
2014
FEMS microbiology letters, 2014, 355(1): 61-70.
Arioli S, Guglielmetti S, Amalfitano S, et al.
Characterization of tetA-like gene encoding for a major facilitator superfamily efflux pump in Streptococcus thermophilus[J].
2014
European Association of National Metrology Institutes
MetVes Report
Yuana Yuana, Rienk Nieuwland
Metrological characterisation of microvesicles from body fluids as non-invasive diagnostic biomarkers
Aug-14
Journal of Extracellular Vesicles 2014, 3: 23262
View paper
Yuana Yuana1, Johannes Levels2, Anita Grootemaat1, Auguste Sturk1 andRienk Nieuwland
Co-isolation of extracellular vesicles and high-densitylipoproteins using density gradient ultracentrifugation
Jul-14
J Thromb Haemost 2014 doi:10.1111/jth.12602
van der Pol E, Coumans FAW, Grootemaat AE, Gardiner C, Sargent IL, Harrison P, Sturk A, van Leeuwen TG, Nieuwland
Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing.
Jun-14
Applied Microbiology doi:10.1111/jam.12528
S. Tamburini, P. Foladori, G. Ferrentino, S. Spilimbergo and O. Jousson
Accurate flow cytometric monitoring of Escherichia coli subpopulations on solid food treated with high pressure carbon dioxide.
Apr-14
British Journal of Haematology doi:10.1111/bjh.12913
Silvia Montoro-Garcia Eduard Shantsila, Diana Hernandez-Romero, Eva Jover, Mariano Valdes, Francisco Marin and Gregory Y. H. Lip
Small-size platelet microparticles trigger platelet and monocyte functionality and modulate thrombogenesis via P-selectin.
17-Mar-14
Microbiology (2013) doi:10.1099/mic.0.063321-0
Sabrina Tamburini, Annalisa Ballarini, Giovanna Ferrentino, Albertomaria Moro, Paola Foladori, Sara Spilimbergo and Olivier Jousson
Comparison of quantitative PCR and flow cytometry as cellular viability methods to study bacterial membrane permeabilization following supercritical CO2 treatment.
J Thromb Haemost 2013; 11 (Suppl. 1): 36-45.
van der Pol E, Coumans F, Varga Z, Krumrey M, Nieuwland R.
Innovation in detection of microparticles and exosomes.
2013
JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY-BLACKWELL, 2013, 11: 22-22.
Van der Pol E, Gardiner C, Harrison P, et al.
Physical interpretation of the size and concentration of extracellular vesicles measured by advanced techniques[C]
2013
J Thromb Haemost 2013; 11 (Suppl. 1): 36-45.
van der Pol E, Coumans F, Varga Z, Krumrey M, Nieuwland R.
Innovation in detection of microparticles and exosomes.
2013
World Journal of Microbiology and Biotechnology, 2013, 29(12): 2417-2428.
Obruca S, Snajdar O, Svoboda Z, et al.
Application of random mutagenesis to enhance the production of polyhydroxyalkanoates by Cupriavidus necator H16 on waste frying oil[J].
2013
BMC Health Services Research 2013, 13:373
Donato Koyalta et al.
Field evaluation in Chad of community usage of CD4 T lymphocyte counting by alternative singleplatform flow cytometry.
2013
BMC Health Services Research doi:10.1186/1472-6963-13-373
Donato Koyalta, Mohammad-Ali Jenabian, Barou Djouater, Noel Djemadji-Oudjeil, Francois-Xavier Mbopi-Keou, Anglique Ndjoyi-Mbiguino, Laurent Blec
Field evaluation in Chad of community usage of CD4 T lymphocyte counting by alternative single-platform flow cytometry
Oct-13
BMC Health Services Research doi:10.1186/1756-0500-6-169
Donato Koyalta, Mohammad-Ali Jenabian, Ngamasra Nadjiouroum, Barou Djouater, Noel Djemadji-Oudjeil, Anglique Ndjoyi-Mbiguino, Laurent Blec
Single-platform, volumetric, CD45-assisted pan-leucogating flow cytometry for CD4 T lymphocytes monitoring of HIV infection according to the WHO recommendations for resource-constrained settings
Apr-13
ChemSusChem 2013, 6, 433 - 436
Federico Aulenta, Simona Rossetti, Stefano Amalfitano, Mauro Majone, Valter Tandoi
Conductive Magnetite Nanoparticles Accelerate the Microbial Reductive Dechlorination of Trichloroethene by Promoting Interspecies Electron Transfer Processes.
10-Feb-13
Atherosclerosis 2013 Jan 29 pii: S0021-9150(13)00064-6 doi: 10.1016/j.atherosclerosis.2013.01.028
Montoro-Garcia S, Shantsila E, Tapp LD, L pez-Cuenca A, Romero AI, Hern ndez-Romero D, Orenes-Pi ero E, Manzano-Fern ndez S, Vald s M, Mar n F, Lip GY
Small-size circulating microparticles in acute coronary syndromes: Relevance to fibrinolytic status, reparative markers and outcomes.
29-Jan-13
Cardiovascular Research, 2012, 93(suppl_1): S92-S127.
Montoro-garcia S, Shantsila E, Lip G.
P578 calcium concentration affects annexin V binding but not phosphatidylserine externalization in microparticles[J].
2012
Nature protocols | VOL.7 NO.7 | 2012 |
Els J van der Vlist et al.
Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry.
2012
J Thromb Haemost 2012; 10: 919-30.
van der Pol E, van Gemert MJC, Sturk A, Nieuwland R, van Leeuwen TG.
Single vs. swarm detection of microparticles and exosomes by flow cytometry.
2012
Thromb Haemost. 2012 Aug;108(2):373-83.
Silvia Montoro-Garcia et al.
An innovative flow cytometric approach for small-size platelet microparticles: influence of calcium.
2012
J Thromb Haemost 2012; 10: 919-30.
van der Pol E, van Gemert MJC, Sturk A, Nieuwland R, van Leeuwen TG.
Single vs. swarm detection of microparticles and exosomes by flow cytometry.
2012
Thromb Haemost 2012; 108.2.
Supplemental data to Montoro-Garcia et al.
An innovative flow cytometric approach for small-size platelet microparticles: Influence of calcium.
2012
Thrombosis and Haemostasis 108.2/2012
Silvia Montoro-Garcia; Eduard Shantsila; Esteban Orenes-Pijero; Maria Luisa Lozano; Gregory Y. H. Lip
An innovative flow cytometric approach for small-size platelet microparticles: Influence of calcium.
11-May-12
Clinical Vaccine Immunology 10.1128/CVI.00023-12
Prof Francois-Xavier Mbopi-Kou
Single-platform, volumetric, CD45 assisted pan-leucogating Auto40 flow cytometer for absolute and percent CD4 T cell counting in resource-constrained settings: Validation in Cameroon.
15-Feb-12
Journal of Translational Medicine doi:10.1186/1479-5876-10-22
Francois-Xavier Mbopi-Kou, Bertrand Sagnia, Jeanne Ngogang, Fru F Angwafo III, Vittorio Colizzi, Luc Montagnier, Laurent Blec
Validation of a single-platform, volumetric, flow cytometry for CD4 T cell count monitoring in therapeutic mobile unit
Feb-12
Journal of Thrombosis and Haemostasis, 2011, 9(8): 1679-1681.
Mullier F, Bailly N, Chatelain C, et al.
More on: calibration for the measurement of microparticles: needs, interests, and limitations of calibrated polystyrene beads for flow cytometry based quantification of biological microparticles[J].
2011
J Thromb Haemost 2011; 9: 1216-24.
Chandler WL, Yeung W, Tait JF.
A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer.
2011
J Thromb Haemost 2011; 9: 1679-81.
Mullier F, Bailly N, Chatelain C, Dogne JM, Chatelain B.
More on: calibration for the measurement of microparticles: needs, interests, and limitations of calibrated polystyrene beads for flow cytometry-based quantification of biological microparticles.
2011
Elsevier Editorial System(tm) for Food Microbiology Manuscript Number: FM-D-11 00332R2
Dr. Jon G. Wilkes, Ph.D. (NCTR); Randal K Tucker, PhD; James A Montgomery; Willie M Cooper, MS; John B Sutherland, PhD; Dan A Buzatu, PhD
Reduction of food matrix interference by a combination of sample preparation and multidimensional gating techniques to facilitate rapid, high sensitivity analysis for Escherichia coli serotype O157 by flow cytometry.
Nov-11
Thrombosis and Haemostasis 2011 Jun 9(6):1216-24
Chandler, W.; Yeung, Wandy; Tait, Jonathan
A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer.
Jun-11
J Immunol Methods 2011 Sep 30; 372(1-2):7-13.
Dieye TN et al
Evaluation of a flow cytometry method for CD4 T cell enumeration based on volumetric primary CD4 gating using thermoresistant reagents.
2011
Seminars in thrombosis and hemostasis. Thieme Medical Publishers, 2010, 36(08): 807-818.
Lacroix R, Robert S, Poncelet P, et al.
Overcoming limitations of microparticle measurement by flow cytometry[C]
2010
Journal of Thrombosis and Haemostasis, 2010, 8(11): 2358-2368.
Shantsila E, Kamphuisen P W, Lip G Y H.
Circulating microparticles in cardiovascular disease: implications for atherogenesis and atherothrombosis[J].
2010
J Thromb Haemost 2010; 8: 2358-68.
Shantsila E, Kamphuisen PW, Lip GYH.
Circulating microparticles in cardiovascular disease: implications for atherogenesis and atherothrombosis.
2010
Semin Thromb Hemost. 2010 Nov;36(8):807-18.
Romaric Lacroix et al.
Overcoming limitations of microparticle measurement by flow cytometry.
2010
White paper (available from ApogeeFlow on request)
Randal Owens, Branch Chief Clinical & Biological Science Latrecia Stubbs, ADH Microbiology Batia Borel, ADH, Microbiology (Cooperation with LITMUS RAPID-B, LLC)
FERN Level 2 Validation Assessment of the LITMUS RAPID-B E. coli O157 Assay with Nine Product Matrices.
Jun-10
Journal of Thrombosis and Haemostasis 8: 1-11
E . SHANTSILA, P . W. KAMPHUISEN* and G. Y. H. LIP
Circulating microparticles in cardiovascular disease: Implications for atherogenesis and atherothrombosis.
2010
Water Research 44 (2010) 3807-3818
P. Foladori, L. Bruni, S. Tamburini, G. Ziglio
Direct quantification of bacterial biomass in influent, effluent and activated sludge of wastewater treatment plants by using flow cytometry.
2010
Seminars in Thrombosis & Haemostasis 36, 8, 807-818
Lacroix et al
Improvement in Resolution of Particles <500nm on new generation flow cytometers
2010
University of Arkansas Medical Sciences (white paper)
Litmus Rapid-B, Marie Chow, PhD Professor of Microbiology and Immunology
Tuberculosis Assay Development Overview.
Nov-08
Water Research 42 (2008) 3757 - 3766
Paola Foladori, Alberto Quaranta, Giuliano Ziglio
Use of silica microspheres having refractive index similar to bacteria for conversion of flow cytometric forward light scatter into biovolume.
2008
WATER RESEARCH 41 (2007) 235 - 243
Paola Foladoria, Bruni Laura, Andreottola, Gianni, Ziglio Giuliano
Effects of sonication on bacteria viability in wastewater treatment plants evaluated by flow cytometry Fecal indicators, wastewater and activated sludge.
2007
PNAS Vol. 104 no. 8, 2939-2944
Magnus Lundgren and Rolf Bernander
Genome-wide transcription map of an archaeal cell cycle.
20-Feb-07
PLOS ONE
View paper
Sebastian Breuert, Thorsten Allers, Gabi Spohn, Jorg Soppa
Regulated Polyploidy in Halophilic Archaea Methanothermobacter thermautotrophicus.
Dec-06
Current Opinion in Microbiology 2005, 8:662-668
Magnus Lundgren and Rolf Bernander
Archaeal cell cycle progress.
Oct-05
Cytometry Part B (Clinical Cytometry) 68B:43-51 (2005)
Silva Barbesti, Laura Soldini, Guisline Carcelain, Angelique Guignet, Vittorio Colizzi, Barbara Mantelli, Alessandro Corvaglia, Thun Tran-Minh, Fernanda Dorigatti, Brigitte Autran, Adriano Lazzarin, and Alberto Beretta
A Simplified Flow Cytometry Method of CD4 And CD8 Cell Counting Based on Thermoresistant Reagents: Implications for Large Scale Monitoring of HIV Infected Patients in Resource Limited Settings.
2005
JOURNAL OF BACTERIOLOGY
Alan I. Majernk, Magnus Lundgren, Paul McDermott, Rolf Bernander and James P. J. Chong
DNA Content and Nucleoid Distribution in Methanothermobacter thermautotrophicus.
Mar-05
APPLIED AND ENVIRONMENTAL MICROBIOLOGY Nov. 2004, p. 6595-6602
Roberto Borghese,1* Francesca Borsetti,1 Paola Foladori,2 Giuliano Ziglio,2 and Davide Zannoni1
Effects of the Metalloid Oxyanion Tellurite (TeO32) on Growth Characteristics of the Phototrophic Bacterium Rhodobacter capsulatus.
Nov-04
Water Research 36 (2002) 460-468
Giuliano Ziglio, Gianni Andreottola, Silvia Barbesti, Giorgio Boschetti, Laura Bruni, Paola Foladori, Roberta Villa
Assessment of activated sludge viability with flow cytometry.
2002

News

  • Mar 2008
    In collaboration with Inodex (France), Apogee exhibited and demonstrated the new 'Auto40' flow cytometer at the '3eme Cours de Retrovirologie Biologique' (3rd March - 2nd April 2008), Dakar, Senegal. This annual course introduces students to the full range of tools and techniques against HIV and attracts world leaders from the scientific community and students from all over west and central Africa.
  • Mar 2007
    New Data Acquisition and Analysis Software (version 1-88) has the ability to overlay data from multiple files.

    This new version has many refinements, but it's main feature is overlaying data from multiple files - a big help when evaluating and presenting your data.
  • Mar 2007
    Apogee presented the A40-MiniFCM to students studying for the "Diplome Universitaire de Retrovirologie Biologique", March 2007, at the CHU Le Dantec Laboratoire de Bacteriologie - Virologie, Dakar.
  • Oct 2006
    Thank you to all who visited our booth at 'Cytometry 2006' - the 11th annual congress of the AFC and the BVAC/ABCA in Bruges, Oct 18-20 (French & Belgium Cytometry Societies).
  • Aug 2006
    "Cell Cycle and Cytoskeletal Elements in Bacteria"

    Apogee sponsored this popular and successful meeting and displayed the high sensitivity A40-MiniFCM. Several of the participants presented data from their Apogee flow cytometers, and others recognised the need for a flow cytometer such as the A40, designed for demanding small particle applications.
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