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Customer Quotations
Dr Hon Leong
London Regional Cancer Program Ontario, Canada
"We have access to other flow cytometers but our microvesicle work demands the sub-micron sensitivity and resolution only offered by ApogeeFlow's A50-Micro. The technical support from ApogeeFlow has always been prompt and effective and the volumetric fluidics and alignment free optics make it easy to use, but above all we chose the A50-Micro because its resolution and sensitivity is outstanding compared to other flow cytometers."
Silvia Montoro-García, PhD
Postdoctoral Research Fellow
1. Centre for Cardiovascular Sciences, University of Birmingham (UK)
2. Department of Cardiology, Hospital Universitario Virgen de la Arrixaca (Murcia, Spain)
"I started my postdoctoral activity at the Centre for Cardiovascular Sciences (University of Birmingham, UK) in June 2010. My main motivations were to identify the biological value of microvesicles in thrombosis and endothelial dysfunction - especially in the context of atherothrombosis. Microparticle (MPs) analysis is very tricky as their small surface poses a problem for discrimination and labelling. My expertise comprises work with different flow cytometers for MPs. Among all the possibilities, we decided to purchase the ApogeeFlow A50-Micro due to its remarkable discrimination of small particles and due to its volumetric sampling system which avoids the need for counting beads. We have developed a new flow cytometric methodology representing a highly specific and reproducible approach when used with the A50-Micro high resolution flow cytometer (CV<6%). The technical support from ApogeeFlow has allowed the fast and efficient deployment of this technique here in Birmingham, which now represents a core technique that we apply on clinical studies of MPs and which is the focus of collaborations with several groups interested in the field."
Dr Stefano Amalfitano
Istituto di Ricerca Sulle Acque (IRSA) del CNR Rome, Italy
"We spent considerable time deciding among all the cytometers on the market. In the end, our choice was ApogeeFlow's A50-Micro. After about two years of use, testing and comparing, I can still say it was the right choice, at least for our research field (aquatic microbiology). It is a powerful and versatile machine for routine analysis and the portability and optical stability are added benefits."
Paola Foladori
University of Trento, Department of Civil and Environmental Engineering
Laura Bruni
Autonomous Province of Trento, Agency for the Treatment of Waste Water
"Our 'A40-Micro' flow cytometer gives the performance we need for measuring small bacteria, assessing their viability and absolute count. It has proven very reliable. After many years of use, we appreciate the high sensitivity not only of the fluorescence signals (for example viability assessment), but also of the light scatter signals."
Researcher, CNRS, France
"The ApogeeFlow A50-Micro has been designed for microbiological applications. It is thus optimized for very small particles such as marine bacteria and viruses. You can [install] a UV laser, very valuable for the analysis of bacteria thanks to dyes such as DAPI or Hoechst. The software is easy to manipulate and very intuitive."
Dutch researcher.
"To be honest, I am truly impressed by both the performance and the solidity of the A50-Micro. To my experience, detection of 100 nm polystyrene beads, after shipping and without optical alignment, is far from trivial for a flow cytometer. I believe there is even room for subtle improvements to optimize the lower detection limit for scattering, for example by illuminating with a 405 nm laser."
Publications
Publication
Authors
Title
Date
Alzheimer's Dement. 2024;1-13
View paper
View paper
Dayarathna T, Roseborough AD, Gomes J, et al.
Nanoscale flow cytometry-based quantification of blood-based extracellular vesicle biomarkers distinguishes MCI and Alzheimer's disease
2024
Cytometry. 2023;103(8):670-83
View paper
View paper
Pink D, Basu A, Wong M, Pham D, Valencia J, Triana V, et al.
Antibody titrations are critical for microflow cytometric analysis of
extracellular vesicles
2023
A.D. Roseborough, Y. Zhu, L. Zhao, S.R. Laviolette, S.H. Pasternak, S.N. Whitehead
Fibrinogen primes the microglial NLRP3 inflammasome and propagates pro-inflammatory signaling via extracellular vesicles: Implications for blood-brain barrier dysfunction
2023
Journal of Neuroinflammation
View paper
View paper
A.D.Roseborough, S.J.Myers, R.Khazaee, Y. Zhu, L.Zhao, E.Iorio, F.M.Elahi, S. H.Pasternak and S.N.Whitehead
Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model
2023
Neurobiology of Disease 177 (2023) 106001
View paper
View paper
A.D. Roseborough, Y. Zhu, L. Zhao, S.R. Laviolette, S.H. Pasternak, S.N. Whitehead
Fibrinogen primes the microglial NLRP3 inflammasome and propagates pro-inflammatory signaling via extracellular vesicles: Implications for blood-brain barrier dysfunction
2023
ACS Earth Space Chem
View paper
View paper
Serge Nader, Alexandre Baccouche, Fiona Connolly, Maya Abou-Ghanem, Sarah A. Styler, John D. Lewis, Desmond Pink, and Sheref S. Mansy
Model Atmospheric Aerosols Convert to Vesicles upon Entry into Aqueous Solution
2022
Robert J Paproski , Desmond Pink , Deborah L Sosnowski , Catalina Vasquez, John D Lewis
Building predictive disease models using extracellular vesicle microscale flow cytometry and machine learning
2022
Roberto Villalobos-Labra , Ricky Liu , Floor Spaans , Tamara Saez , Anita Quon, Michael Wong , Desmond Pink , John Lewis , Manu Vatish , Sandra T Davidge, Christy-Lynn M Cooke
Placenta-Derived Extracellular Vesicles from Preeclamptic and Healthy Pregnancies Impair ex vivo Vascular Endothelial Function
2022
Nanoscale, 2022, 14, 9781
Yohan Kim, Edwin van der Pol, Ali Arafa, Ishwor Thapa, Cameron J. Britton, Jorgena Kosti, Siyang Song, Vidhu B. Joshi, Ree M. Erickson, Hesham Alie, Fabrice Lucien
Calibration and standardization of extracellular vesicle measurements by flow cytometry for translational prostate cancer research
2022
Biomedicines 2021, 9, 124.
View paper
View paper
Jaco Botha, Haley R. Pugsley, Aase Handberg
Conventional, High-Resolution and Imaging Flow Cytometry: Benchmarking Performance in Characterisation of Extracellular Vesicles
2021
Platelets31.2 (2020): 206-214.
Rosinska, Justyna, et al.
"Effect of acetylsalicylic acid intake on platelet derived microvesicles in healthy subjects."
2020
PLoS ONE 15(8)
Palviainen M, Saraswat M, Varga Z, Kitka D, Neuvonen M, Puhka M, et al.
Extracellular vesicles from human plasma and serum are carriers of extravesicular cargo. Implications for biomarker discovery.
2020
Cells, 2020
J Karkowska-Kuleta, K Kulig, E Karnas, E Zuba-Surma
Characteristics of Extracellular Vesicles Released by the Pathogenic Yeast-Like Fungi Candida glabrata, Candida parapsilosis and Candida tropicalis
2020
bioRxiv (2020).
Cooper, Tyler T., et al.
"Ultrafiltration Segregates Tissue Regenerative Stimuli Harboured Within and Independent of Extracellular Vesicles."
2020
Gastroenterology (2020)
Dasgupta D et al.
IRE1A Stimulates Hepatocyte-derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis
2020
Front. Oncol., 04 June 2020
L. G. Rikkert et al.
Cancer-ID: Toward Identification of Cancer by Tumor-Derived Extracellular Vesicles in Blood.
2020
Brain. 2020 May 1;143(5):1476-1497.
Min Guo et al.
Microglial Exosomes Facilitate synuclein Transmission in Parkinson's Disease.
2020
PLoS ONE 15(6): e0233443.
Rikkert LG, de Rond L, van Dam A, van Leeuwen TG, Coumans FAW, de Reijke TM, et al.(2020)
Detection of extracellular vesicles in plasma and urine of prostate cancer patients by flow cytometry and surface plasmon resonance imaging.
2020
Platelets, 2020, 31(1): 26-32.
Gasecka A, Nieuwland R, Budnik M, et al.
Randomized controlled trial protocol to investigate the antiplatelet therapy effect on extracellular vesicles (AFFECT EV) in acute myocardial infarction[J].
2020
bioRxiv, 2020
Maia J, Batista S, Couto N, et al.
Population Analysis of Extracellular Vesicles in Microvolumes of Biofluids[J].
2020
Neuro-Oncology, Volume 22, Issue 7, July 2020, Pages 967-978
Benjamin T. Himes et al.
The role of extracellular vesicles and PD-L1 in glioblastoma-mediated immunosuppressive monocyte induction.
2020
Mitochondrion 8 August 2020
Olivia R.Stephens et al.
Characterization and origins of cell-free mitochondria in healthy murine and human blood.
2020
Cell Death Dis 11, 677 (2020).
Gidlof, O., Bader, K., Celik, S. et al.
Inhibition of the long non-coding RNA NEAT1 protects cardiomyocytes from hypoxia in vitro via decreased pri-miRNA processing.
2020
BMC Ophthalmology volume 20, Article number: 233 (2020)
Zhong-Fang Yuan et al.
MicroRNA-182-5p protects human lens epithelial cells against oxidative stress-induced apoptosis by inhibiting NOX4 and p38 MAPK signalling.
2020
Colloids and Surfaces B: Biointerfaces (2020)
Hou Y-chen, Li J-an, Zhu S-jie, Cao C, Tang J-nan, Zhang J-ying, Guan S-kang
Tailoring of cardiovascular stent material surface by immobilizing exosomes for better pro-endothelialization function
2020
Desmond Pink, Michael Wong, Diana Pham, Renjith Pillai , Leanne Stifanyk, Sylvia Koch, Rebecca Hiebert, Oliver Kenyon, John Lewis
Performance Qualification for Micro Flow Cytometers: Understanding technical limitations to improve your research
Jul-20
THE JOURNAL OF UROLOGY 1 Apr 2019
Fabrice Lucien-Matteoni et al.
NEXT-GENERATION LIQUID BIOPSIES USING EXTRACELLULAR VESICLE DETECTION BY NANOSCALE FLOW CYTOMETRY.
2019
Journal of hepatology, 2019, 71(6): 1193-1205.
Guo Q, Furuta K, Lucien F, et al.
Integrin 1-enriched extracellular vesicles mediate monocyte adhesion and promote liver inflammation in murine NASH[J].
2019
ournal of extracellular vesicles, 2019, 8(1): 1643671
de Rond L, Libregts S, Rikkert L G, et al.
Refractive index to evaluate staining specificity of extracellular vesicles by flow cytometry[J].
2019
Journal of extracellular vesicles, 2019, 8(1): 1629865
Zeng Y, Yao X, Liu X, et al.
Anti-angiogenesis triggers exosomes release from endothelial cells to promote tumor vasculogenesis[J].
2019
Journal of diabetes research, 2019
Hohendorff J, Drozdz A, Borys S, et al.
Effects of Negative Pressure Wound Therapy on Levels of Angiopoetin-2 and Other Selected Circulating Signaling Molecules in Patients with Diabetic Foot Ulcer[J].
2019
The Journal of Immunology, 2019, 203(7): 1961-1972.
Hao Q, Gudapati V, Monsel A, et al.
Mesenchymal Stem Cell Derived Extracellular Vesicles Decrease Lung Injury in Mice[J].
2019
International Society for Extracellular Vesicles Annual Meeting 2019. 2019, 8(Suppl. 1).
Rasmussen R W, Botha J, Sanden M, et al.
Lipoprotein particles can be detected by high-resolution flow cytometry and potentially interfere with EV characterization[C]
2019
Transfusion, 2019, 59(1): 134-145.
Wirtz M R, Jurgens J, Zuurbier C J, et al.
Washing or filtering of blood products does not improve outcome in a rat model of trauma and multiple transfusion[J].
2019
The Journal of Urology, 2019, 201(Supplement 4): e179-e179.
Lucien-Matteoni* F, Gomes J, Brar H, et al.
Mp13-07 next-generation liquid biopsies using extracellular vesicle detection by nanoscale flow cytometry[j].
2019
The Prostate, 2019, 79(15): 1767-1776.
Joncas F H, Lucien F, Rouleau M, et al.
Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients[J].
2019
van Manen L, Peters A L, van der Sluijs P M, et al.
Clearance and phenotype of extracellular vesicles after red blood cell transfusion in a human endotoxemia model[J].
2019
European Heart Journal, 2019, 40(Supplement_1): ehz747. 0073.
Gasecka A, Nieuwland R, Budnik M, et al.
257 Ticagrelor decreases concentrations of prothrombotic extracellular vesicles compared to clopidogrel[J].
2019
Frontiers in oncology, 2019, 9: 651.
Cumba Garcia L M, Peterson T E, Cepeda M A, et al.
Isolation and analysis of plasma-derived exosomes in patients with glioma[J].
2019
Oncotarget, 2019, Vol. 10, (No. 10), pp: 1045-1055.
Lucien F, Lac V, Billadeau D D, et al.
Glypican-1 and glycoprotein 2 bearing extracellular vesicles do not discern pancreatic cancer from benign pancreatic diseases[J].
2019
Microcirculation, 2019, 26(1): e12515.
Li B, Li L, Zhang Q, et al.
Effects of tumor necrosis factor induced exosomes on the endothelial cellular behavior, metabolism and bioenergetics[J].
2019
Clinical Kidney Journal, 2019.
Uil M, Hau C M, Ahdi M, et al.
Cellular origin and microRNA profiles of circulating extracellular vesicles in different stages of diabetic nephropathy[J].
2019
Hepatology communications, 2019, 3(9): 1235-1249.
Li J, Liu H, Mauer A S, et al.
Characterization of cellular sources and circulating levels of extracellular vesicles in a dietary murine model of nonalcoholic steatohepatitis[J].
2019
Thrombosis research, 2019, 176: 18-26.
Rosiska J, Ambrosius W, Maciejewska J, et al.
Association of platelet-derived microvesicles and their phenotypes with carotid atherosclerosis and recurrent vascular events in patients after ischemic stroke[J].
2019
Journal of extracellular vesicles, 2019, 8(1): 1688936.
Berckmans R J, Lacroix R, Hau C M, et al.
Extracellular vesicles and coagulation in blood from healthy humans revisited[J].
2019
The Prostate, 2019, 79(6): 592-603.
Padda R S, Deng F K, Brett S I, et al.
Nanoscale flow cytometry to distinguish subpopulations of prostate extracellular vesicles in patient plasma[J].
2019
Thorax, 2019, 74(1): 43-50.
Park J, Kim S, Lim H, et al.
Therapeutic effects of human mesenchymal stem cell microvesicles in an ex vivo perfused human lung injured with severe E. coli pneumonia[J].
2019
Artificial Cells, Nanomedicine, and Biotechnology, (2019) 47:1, 2918-2929
Rui Ren et al.
Bone marrow mesenchymal stem cell-derived exosome uptake and retrograde transport can occur at peripheral nerve endings
2019
J. Vis. Exp. (144), e59128, (2019).
Balbi, C., Bolis, S., Vassalli, G., Barile, L.
Flow Cytometric Analysis of Extracellular Vesicles from Cell-conditioned Media.
2019
Proteomes. 2019 Apr 25;7(2):17
Helena Kupcova Skalnikova et al.
Isolation and Characterization of Small Extracellular Vesicles from Porcine Blood Plasma, Cerebrospinal Fluid, and Seminal Plasma.
2019
Curr Protoc Stem Cell Biol. 2019 Feb;48(1):e76.
Cansu Gorgun et al.
Isolation and Flow Cytometry Characterization of Extracellular-Vesicle Subpopulations Derived from Human Mesenchymal Stromal Cells.
2019
HREBA.CC-18-0241 Version 2.0 April 10 2019
Adrian Fairey et al.
Clinical Validation of ClarityDX Prostate as a reflex test to PSA to refine the prediction of clinically significant prostate cancer. APCaRI-05
2019
Biomacromolecules 2019, 20, 9, 3592-3600
Jiwei Cui et al.
Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake.
2019
Pharmacological Research 141 (2019) 214-223
Maryam Baeeri et al.
-Lipoic acid prevents senescence, cell cycle arrest, and inflammatory cues in fibroblasts by inhibiting oxidative stress.
2019
Adv. Healthcare Mater. 2019
Jiwei Cui et al.
Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies.
2019
Mutat Res Gen Tox En 845 (2019)
Alena Opattova et al.
Ganoderma Lucidum induces oxidative DNA damage and enhances the effect of 5-Fluorouracil in colorectal cancer in vitro and in vivo.
2019
Journal of Controlled Release 307 (2019) 355-367
Matthew Faria et al.
Revisiting cell particle association in vitro: A quantitative method to compare particle performance.
2019
Iran J Basic Med Sci 2019; 22:445-451
Mohammadi P, Rahimifard M, Baeeri M, Abdollahi M, Mostafalou S.
Mechanistic assessment of cadmium toxicity in association with the functions of estrogen receptors in the Langerhans islets.
2019
J Thromb Haemost. 2019 Dec 12 doi: 10.1111/jth.14689
Gasecka A, Nieuwland R, Budnik M, Dignat-George F, Eyileten C, Harrison P, Lacroix R, Leroyer A, Opolski G, Pluta K, van der Pol E, Postua M, Siljander P, Siller-Matula JM, Filipiak KJ
Ticagrelor attenuates the increase of extracellular vesicle concentrations in plasma after acute myocardial infarction compared to clopidogrel
Dec-19
Platelets
Poznan University of Medical Sciences, Poznan, Poland: Justyna Rosinska, Joanna Maciejewska, Robert Narozny, Krystyna Osztynowicz, Beata Raczak, Slawomir Michalak, Cezary Watala, Wojciech Kozubski, Maria Lukasik
Effect of acetylsalicylic acid intake on platelet derived microvesicles in healthy subjects
Mar-19
Thrombosis Research
Poznan University of Medical Sciences, Poznan, Poland: Justyna Rosinska, Wojciech Ambrosius, Joanna Maciejewska, Robert Narozny, Wojciech Kozubski, Maria Lukasik
Association of platelet-derived microvesicles and their phenotypes with carotid atherosclerosis and recurrent vascular events in patients after ischemic stroke
Feb-19
International Journal of Medical Sciences 2019, 16(2): 264-275 doi: 10.7150/ijms.28580
Bernadeta Chyrchel, Anna Drod, Dorota Dugosz, Ewa Stpie, Andrzej Surdacki
Platelet Reactivity And Circulating Platelet-Derived Microvesicles Are Differently Affected By P2Y12 Receptor Antagonists
Jan-19
Transfusion. 2018 Jun;58(6):1486-1493
Anna L. Peters et al.
Transfusion of autologous extracellular vesicles from stored red blood cells does not affect coagulation in a model of human endotoxemia.
2018
Int Orthop. 2018 Dec;42(12):2865-2872.
Ye Zhao et al.
Synovial fluid-derived exosomal lncRNA PCGEM1 as biomarker for the different stages of osteoarthritis.
2018
bioRxiv Apr. 29, 2018
Desmond Pink, Julien Donnelier, John Lewis, Janice E. A. Braun.
Cargo-Loading of Misfolded Proteins into Extracellular Vesicles: The Role of J Proteins.
2018
Journal of Thrombosis and Haemostasis Volume 16, Issue 8 (2018)
Z. Varga et al.
Hollow organosilica beads as reference particles for optical detection of extracellular vesicles.
2018
bioRxiv, 2018: 476226.
Russell J C, Merrihew G E, Robbins J E, et al.
Isolation and characterization of extracellular vesicles from Caenorhabditis elegans for multi-omic analysis[J].
2018
Sci Rep. 2018; 8: 5426.
Ferenc Kovics et al.
The impact of circulating preeclampsia-associated extracellular vesicles on the migratory activity and phenotype of THP-1 monocytic cells.
2018
Arizona State University, 2018.
Zhong Z.
Molecular Profiling Plasma Extracellular Vesicles from Breast Cancer Patients[D].
2018
Frontiers in cardiovascular medicine, 2018, 5: 156.
Sanden M, Botha J, Nielsen M R S, et al.
BLTR1 and CD36 expressing microvesicles in atherosclerotic patients and healthy individuals[J].
2018
International journal of nanomedicine 13 (2018): 1653.
Dabrowska, Sylwia, et al.
"Imaging of extracellular vesicles derived from human bone marrow mesenchymal stem cells using fluorescent and magnetic labels."
2018
British Journal of Biomedical Science just-accepted (2018): 1-19.
Heitmar, R., et al.
"The relationship of systemic markers of haemostasis with retinal blood vessel responses in cardiovascular disease and/or diabetes."
2018
Journal of Thrombosis and Haemostasis (2018).
Yu, Y., et al.
"Extracellular vesicles from human saliva promote haemostasis by delivering coagulant tissue factor to activated platelets."
2018
Biochemical and biophysical research communications, 2018, 503(3): 1278-1283.
Zhang J, Wang W, Chen S, et al.
Distinct non-invasive evaluation values of tumor-derived cell-free microRNAs, circulating microvesicles and exosomal microRNAs after renal carcinoma cryoablation[J].
2018
Thrombosis and haemostasis, 2018, 118(06): 990-1000.
Yu Y, Buing A N, Hau C M, et al.
Tissue Factor Coagulant Activity is Regulated by the Plasma Membrane Microenvironment[J].
2018
Journal of extracellular vesicles, 2018, 7(1): 1458574.
Zhong Z, Rosenow M, Xiao N, et al.
Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion[J].
2018
British Journal of Biomedical Science, 2018 (just-accepted): 1-19.
Heitmar R, Nicholl P, Lee B, et al.
The relationship of systemic markers of haemostasis with retinal blood vessel responses in cardiovascular disease and/or diabetes[J].
2018
Breast cancer research and treatment, 2018: 1-10.
Garre E G, Gil G L, Garcia S M, et al.
Circulating small-sized endothelial microparticles as predictors of clinical outcome after chemotherapy for breast cancer: an exploratory analysis[J].
2018
Thromb Haemost. 2018 Sep;118(9):1612-1624.
Janice Gomes et al.
Analytical Considerations in Nanoscale Flow Cytometry of Extracellular Vesicles to Achieve Data Linearity.
2018
Synaptosomes. Humana Press, New York, NY, 2018: 297-310.
Postupna N O, Latimer C S, Keene C D, et al.
Flow Cytometric Evaluation of Crude Synaptosome Preparation as a Way to Study Synaptic Alteration in Neurodegenerative Diseases[M]
2018
J Thromb Haemost 2018; 16:1236-45.
van der Pol E, Sturk A, van Leeuwen T, Nieuwland R, Coumans F, for the ISTH-SSC-VB Working group.
Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation.
2018
RNA biology, 2018 (just-accepted): 1-21.
Guo T, Han W, She Q.
Tolerance of Sulfolobus SMV1 virus to the immunity of IA and III-B CRISPR-Cas systems in Sulfolobus islandicus[J].
2018
Use of Nanoparticles in Neuroscience. Humana Press, New York, NY, 2018: 251-267.
Kaszewski J, Kiebik P, Soska-Zielonka A, et al.
Long-Term Organism Distribution of Microwave Hydrothermally Synthesized ZrO 2: Pr Nanoparticles[M]
2018
ACS applied materials & interfaces, 2018.
Cherepanov P V, Rahim M A, Bertleff-Zieschang N, et al.
Electrochemical Behavior and Redox-Dependent Disassembly of Gallic Acid/FeIII Metal Phenolic Networks[J].
2018
Nanoscale, 2018.
Bertucci A, Guo J, Oppmann N, et al.
Probing transcription factor binding activity and downstream gene silencing in living cells with a DNA nanoswitch[J].
2018
Toxicology and applied pharmacology, 2018, 342: 86-98.
Sanadgol N, Golab F, Mostafaie A, et al.
Low, but not high, dose triptolide controls neuroinflammation and improves behavioral deficits in toxic model of multiple sclerosis by dampening of NF-B activation and acceleration of intrinsic myelin repair[J].
2018
Polymer Chemistry, 2018.
Zhang Y, Jiang Q, Wojnilowicz M, et al.
Acid-sensitive poly (-cyclodextrin)-based multifunctional supramolecular gene vector[J].
2018
Small 2018, 1802342
Quinn A. Besford et al.
Self-Assembled Metal Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles.
2018
Magdalena Surmana, Dorota Hoja-ukowicza, Sabina Szweda, Anna Drodb, Ewa Stpie, Magorzata Przybyio
Human melanoma-derived ectosomes are enriched with specific glycan epitopes
Jun-18
Preprint: View paper
Desmond Pink, Julien Donnelier, John Lewis, Janice E.A. Braun
Cargo-Loading of Misfolded Proteins into Extracellular Vesicles: The Role of J Proteins
Apr-18
J. of Thrombosis & Haemostasis, 16: 1-10 doi: 10.1111/jth.14009
E . Van Der Pol, A. Sturk, T. Van Leeuwen, R. Nieuwland, F. Coumans for the ISTH-SSC-VB Working Group
Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation
Feb-18
American Association for Clinical Chemistry doi:10.1373/clinchem.2017.278978
Leonie de Rond, Edwin van der Pol, Chi M. Hau, Zoltan Varga, Auguste Sturk, Ton G. van Leeuwen, Rienk Nieuwland, Frank A.W. Coumans
Comparison of Generic Fluorescent Markers for Detection of Extracellular Vesicles by Flow Cytometry
Feb-18
Nanomedicine: Nanotechnology, Biology, and Medicine doi:10.1016/j.nano.2017.12.012
Edwin van der Pol, Leonie de Rond, Frank A.W. Coumans, Elmar L. Gool, Anita N. Bing, Auguste Sturk, Rienk Nieuwland, Ton G. van Leeuwen
Absolute sizing and label-free identification of extracellular vesicles by flow cytometry
Jan-18
Cancer Research, 2017, 77(1): 3-13.
Paproski R J, Jovel J, Wong G K S, et al.
Enhanced detection of cancer biomarkers in blood-borne extracellular vesicles using nanodroplets and focused ultrasound[J].
2017
Scientific reports, 2017, 7: 42741.
Domenyuk V, Zhong Z, Stark A, et al.
Plasma exosome profiling of cancer patients by a next generation systems biology approach[J].
2017
European Journal of Pharmaceutical Sciences, 2017, 98: 4-16.
Valkonen S, Van der Pol E, Bing A, et al.
Biological reference materials for extracellular vesicle studies[J].
2017
Translational Cancer Research, 2017, 6(3): 599-612.
Guo L, He B.
Extracellular vesicles and their diagnostic and prognostic potential in cancer[J].
2017
Clinical chemistry, 2017, 63(10): 1633-1641.
Gool E L, Stojanovic I, Schasfoort R B M, et al.
Surface plasmon resonance is an analytically sensitive method for antigen profiling of extracellular vesicles[J].
2017
2017
Pink D, Paproski R, Sosnowski D, et al.
Technical validation of a micro-flow cytometry platform for prostate cancer biomarker discovery [J].
2017
Journal of extracellular vesicles, 2017, 6(1): 1354645.
Lazaro-Ibez E, Neuvonen M, Takatalo M, et al.
Metastatic state of parent cells influences the uptake and functionality of prostate cancer cell-derived extracellular vesicles[J].
2017
Journal of thrombosis and thrombolysis, 2017, 43(1): 18-23.
Lau Y C, Xiong Q, Blann A D, et al.
Relationship between renal function and circulating microparticles, soluble P-selectin and E-selectin levels in atrial fibrillation[J].
2017
Transfusion, 2017, 57(6): 1459-1469.
Black A, Ors E, Kelsch R, et al.
Analysis of platelet derived extracellular vesicles in plateletpheresis concentrates: a multicenter study[J].
2017
Frontiers in cellular and infection microbiology, 2017, 7: 351.
Fleetwood A J, Lee M K S, Singleton W, et al.
Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles[J].
2017
Frontiers in immunology, 2017, 8: 1017.
Cecil J D, O'Brien-Simpson N M, Lenzo J C, et al.
Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo[J].
2017
Cancer Research Frontiers, 2017, 3(1): 83-111.
Tatischeff I.
Prostate Cancer under the Light of Tumor Cells-derived Extracellular Vesicles[J].
2017
The Prostate, 2017, 77(13): 1335-1343.
Brett S I, Lucien F, Guo C, et al.
Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples[J].
2017
2017
Brar H S.
Triple Positive Microparticles as a 'Liquid Biopsy' for Risk Stratification of Prostate Cancer[J].
2017
Extracellular Vesicles. Humana Press, New York, NY, 2017: 175-190.
Camacho V, Toxavidis V, Tigges J C.
Characterization of Extracellular Vesicles by Flow Cytometry[M]
2017
Drug testing and analysis, 2017.
Voss S C, Jaganjac M, Al Thani A M, et al.
Analysis of RBC Microparticles in stored whole blood bags - a promising marker to detect blood doping in sports? [J].
2017
2017
Pereira H M G, Sardela V F, Padilha M C, et al.
Report Sport doping and medicine[J]
2017
Int J Clin Exp Pathol. 2017; 10(8): 8383-8388.
Yingge Wang et al.
Circulating exosomes and exosomal lncRNA HIF1A-AS1 in atherosclerosis.
2017
Journal of Microcirculation, 2017, 27(2): 8-12
Zhang Honggang and others
Essential hypertensive rats plasma exosomes level and its correlation with microcirculation changes.
2017
J Thromb Haemost 2017; 15: 187-93.
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ChemSusChem 2013, 6, 433 - 436
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Thrombosis and Haemostasis 108.2/2012
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An innovative flow cytometric approach for small-size platelet microparticles: Influence of calcium.
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Clinical Vaccine Immunology 10.1128/CVI.00023-12
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15-Feb-12
Journal of Translational Medicine doi:10.1186/1479-5876-10-22
Francois-Xavier Mbopi-Kou, Bertrand Sagnia, Jeanne Ngogang, Fru F Angwafo III, Vittorio Colizzi, Luc Montagnier, Laurent Blec
Validation of a single-platform, volumetric, flow cytometry for CD4 T cell count monitoring in therapeutic mobile unit
Feb-12
Journal of Thrombosis and Haemostasis, 2011, 9(8): 1679-1681.
Mullier F, Bailly N, Chatelain C, et al.
More on: calibration for the measurement of microparticles: needs, interests, and limitations of calibrated polystyrene beads for flow cytometry based quantification of biological microparticles[J].
2011
J Thromb Haemost 2011; 9: 1216-24.
Chandler WL, Yeung W, Tait JF.
A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer.
2011
J Thromb Haemost 2011; 9: 1679-81.
Mullier F, Bailly N, Chatelain C, Dogne JM, Chatelain B.
More on: calibration for the measurement of microparticles: needs, interests, and limitations of calibrated polystyrene beads for flow cytometry-based quantification of biological microparticles.
2011
Elsevier Editorial System(tm) for Food Microbiology Manuscript Number: FM-D-11 00332R2
Dr. Jon G. Wilkes, Ph.D. (NCTR); Randal K Tucker, PhD; James A Montgomery; Willie M Cooper, MS; John B Sutherland, PhD; Dan A Buzatu, PhD
Reduction of food matrix interference by a combination of sample preparation and multidimensional gating techniques to facilitate rapid, high sensitivity analysis for Escherichia coli serotype O157 by flow cytometry.
Nov-11
Thrombosis and Haemostasis 2011 Jun 9(6):1216-24
Chandler, W.; Yeung, Wandy; Tait, Jonathan
A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer.
Jun-11
J Immunol Methods 2011 Sep 30; 372(1-2):7-13.
Dieye TN et al
Evaluation of a flow cytometry method for CD4 T cell enumeration based on volumetric primary CD4 gating using thermoresistant reagents.
2011
Seminars in thrombosis and hemostasis. Thieme Medical Publishers, 2010, 36(08): 807-818.
Lacroix R, Robert S, Poncelet P, et al.
Overcoming limitations of microparticle measurement by flow cytometry[C]
2010
Journal of Thrombosis and Haemostasis, 2010, 8(11): 2358-2368.
Shantsila E, Kamphuisen P W, Lip G Y H.
Circulating microparticles in cardiovascular disease: implications for atherogenesis and atherothrombosis[J].
2010
J Thromb Haemost 2010; 8: 2358-68.
Shantsila E, Kamphuisen PW, Lip GYH.
Circulating microparticles in cardiovascular disease: implications for atherogenesis and atherothrombosis.
2010
Semin Thromb Hemost. 2010 Nov;36(8):807-18.
Romaric Lacroix et al.
Overcoming limitations of microparticle measurement by flow cytometry.
2010
White paper (available from ApogeeFlow on request)
Randal Owens, Branch Chief Clinical & Biological Science Latrecia Stubbs, ADH Microbiology Batia Borel, ADH, Microbiology (Cooperation with LITMUS RAPID-B, LLC)
FERN Level 2 Validation Assessment of the LITMUS RAPID-B E. coli O157 Assay with Nine Product Matrices.
Jun-10
Journal of Thrombosis and Haemostasis 8: 1-11
E . SHANTSILA, P . W. KAMPHUISEN* and G. Y. H. LIP
Circulating microparticles in cardiovascular disease: Implications for atherogenesis and atherothrombosis.
2010
Water Research 44 (2010) 3807-3818
P. Foladori, L. Bruni, S. Tamburini, G. Ziglio
Direct quantification of bacterial biomass in influent, effluent and activated sludge of wastewater treatment plants by using flow cytometry.
2010
Seminars in Thrombosis & Haemostasis 36, 8, 807-818
Lacroix et al
Improvement in Resolution of Particles <500nm on new generation flow cytometers
2010
University of Arkansas Medical Sciences (white paper)
Litmus Rapid-B, Marie Chow, PhD Professor of Microbiology and Immunology
Tuberculosis Assay Development Overview.
Nov-08
Water Research 42 (2008) 3757 - 3766
Paola Foladori, Alberto Quaranta, Giuliano Ziglio
Use of silica microspheres having refractive index similar to bacteria for conversion of flow cytometric forward light scatter into biovolume.
2008
WATER RESEARCH 41 (2007) 235 - 243
Paola Foladoria, Bruni Laura, Andreottola, Gianni, Ziglio Giuliano
Effects of sonication on bacteria viability in wastewater treatment plants evaluated by flow cytometry Fecal indicators, wastewater and activated sludge.
2007
PNAS Vol. 104 no. 8, 2939-2944
Magnus Lundgren and Rolf Bernander
Genome-wide transcription map of an archaeal cell cycle.
20-Feb-07
PLOS ONE
View paper
View paper
Sebastian Breuert, Thorsten Allers, Gabi Spohn, Jorg Soppa
Regulated Polyploidy in Halophilic Archaea Methanothermobacter thermautotrophicus.
Dec-06
Current Opinion in Microbiology 2005, 8:662-668
Magnus Lundgren and Rolf Bernander
Archaeal cell cycle progress.
Oct-05
Cytometry Part B (Clinical Cytometry) 68B:43-51 (2005)
Silva Barbesti, Laura Soldini, Guisline Carcelain, Angelique Guignet, Vittorio Colizzi, Barbara Mantelli, Alessandro Corvaglia, Thun Tran-Minh, Fernanda Dorigatti, Brigitte Autran, Adriano Lazzarin, and Alberto Beretta
A Simplified Flow Cytometry Method of CD4 And CD8 Cell Counting Based on Thermoresistant Reagents: Implications for Large Scale Monitoring of HIV Infected Patients in Resource Limited Settings.
2005
JOURNAL OF BACTERIOLOGY
Alan I. Majernk, Magnus Lundgren, Paul McDermott, Rolf Bernander and James P. J. Chong
DNA Content and Nucleoid Distribution in Methanothermobacter thermautotrophicus.
Mar-05
APPLIED AND ENVIRONMENTAL MICROBIOLOGY Nov. 2004, p. 6595-6602
Roberto Borghese,1* Francesca Borsetti,1 Paola Foladori,2 Giuliano Ziglio,2 and Davide Zannoni1
Effects of the Metalloid Oxyanion Tellurite (TeO32) on Growth Characteristics of the Phototrophic Bacterium Rhodobacter capsulatus.
Nov-04
Water Research 36 (2002) 460-468
Giuliano Ziglio, Gianni Andreottola, Silvia Barbesti, Giorgio Boschetti, Laura Bruni, Paola Foladori, Roberta Villa
Assessment of activated sludge viability with flow cytometry.
2002
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